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中华肝脏外科手术学电子杂志 ›› 2015, Vol. 04 ›› Issue (01) : 57 -59. doi: 10.3877/cma.j.issn.2095-3232.2015.01.016

所属专题: 文献

综述

自噬在肝细胞癌中的研究进展
赵坤1, 叶小鸣1,()   
  1. 1. 510530 广州,中山大学附属第三医院岭南医院普通外科
  • 收稿日期:2014-10-08 出版日期:2015-02-10
  • 通信作者: 叶小鸣
  • 基金资助:
    国家自然科学基金(81302550)

Recent research development of autophagy in hepatocellular carcinoma

Kun Zhao1, Xiaoming Ye1()   

  • Received:2014-10-08 Published:2015-02-10
  • Corresponding author: Xiaoming Ye
引用本文:

赵坤, 叶小鸣. 自噬在肝细胞癌中的研究进展[J]. 中华肝脏外科手术学电子杂志, 2015, 04(01): 57-59.

Kun Zhao, Xiaoming Ye. Recent research development of autophagy in hepatocellular carcinoma[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2015, 04(01): 57-59.

[1]
Ge YY, Shi Q, Zheng ZY, et al. MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R[J]. Oncotarget, 2014, 5(15):6218-6228.
[2]
Qiu DM, Wang GL, Chen L, et al. The expression of beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance[J]. BMC Cancer, 2014 (14):327.
[3]
Rubinsztein DC, Codogno P, Levine B. Autophagy modulation as a potential therapeutic target for diverse diseases[J]. Nat Rev Drug Discov, 2012, 11(9):709-730.
[4]
Wang Z, Han W, Sui X, et al. Autophagy: a novel therapeutic target for hepatocarcinoma (review)[J]. Oncol Lett, 2014, 7(5):1345-1351.
[5]
Scharl M, Rogler G. Inflammatory bowel disease: dysfunction of autophagy?[J]. Dig Dis, 2012, 30 Suppl 3:12-19.
[6]
Eskelinen EL. The dual role of autophagy in cancer[J]. Curr Opin Pharmacol, 2011, 11(4):294-300.
[7]
Yamaguchi O, Otsu K. Role of autophagy in aging[J]. J Cardiovasc Pharmacol, 2012, 60(3):242-247.
[8]
Bao L, Chandra PK, Moroz K, et al. Impaired autophagy response in human hepatocellular carcinoma[J]. Exp Mol Pathol, 2014, 96(2):149-154.
[9]
Lee YJ, Hah YJ, Kang YN, et al. The autophagy-related marker LC3 can predict prognosis in human hepatocellular carcinoma[J]. PLoS One, 2013, 8(11):e81540.
[10]
White E, Karp C, Strohecker AM, et al. Role of autophagy in suppression of inflammation and cancer[J]. Curr Opin Cell Biol, 2010, 22(2):212-217.
[11]
Liang C, Jung JU. Autophagy genes as tumor suppressors[J]. Curr Opin Cell Biol, 2010, 22(2):226-233.
[12]
Quan W, Lee MS. Role of autophagy in the control of body metabolism[J]. Endocrinol Metab, 2013, 28(1):6-11.
[13]
Maycotte P, Thorburn A. Targeting autophagy in breast cancer[J]. World J Clin Oncol, 2014, 5(3):224-240.
[14]
Nguyen HG, Yang JC, Kung HJ, et al. Targeting autophagy overcomes enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model[J]. Oncogene, 2014, 33(36):4521-4530.
[15]
Selvakumaran M, Amaravadi RK, Vasilevskaya IA, et al. Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy[J]. Clin Cancer Res, 2013, 19(11):2995-3007.
[16]
Dong M, Wan XB, Yuan ZY, et al. Low expression of Beclin 1 and elevated expression of HIF-1alpha refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer[J]. Med Oncol, 2013, 30(1):355.
[17]
Cai M, Hu Z, Liu J, et al. Beclin 1 expression in ovarian tissues and its effects on ovarian cancer prognosis[J]. Int J Mol Sci, 2014, 15(4):5292-5303.
[18]
Liu C, Xu P, Chen D, et al. Roles of autophagy-related genes Beclin-1 and LC3 in the development and progression of prostate cancer and benign prostatic hyperplasia[J]. Biomed Rep, 2013, 1(6):855-860.
[19]
He S, Ni D, Ma B, et al. PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex[J]. Nat Cell Biol, 2013, 15(10):1206-1219.
[20]
Zhao Z, Ni D, Ghozalli I, et al. UVRAG: at the crossroad of autophagy and genomic stability[J]. Autophagy, 2012, 8(9):1392-1393.
[21]
Dolganiuc A, Thomes PG, Ding WX, et al. Autophagy in alcohol-induced liver diseases[J]. Alcohol Clin Exp Res, 2012, 36(8):1301-1308.
[22]
Ni HM, Williams JA, Yang H, et al. Targeting autophagy for the treatment of liver diseases[J]. Pharmacol Res, 2012, 66(6):463-474.
[23]
Cui J, Gong Z, Shen HM. The role of autophagy in liver cancer: molecular mechanisms and potential therapeutic targets[J]. Biochim Biophys Acta, 2013, 1836(1):15-26.
[24]
He Z, Liu H, Agostini M, et al. P73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene[J]. Cell Death Differ, 2013, 20(10):1415-1424.
[25]
Sir D, Kuo CF, Tian Y, et al. Replication of hepatitis C virus RNA on autophagosomal membranes[J]. J Biol Chem, 2012, 287(22):18036-18043.
[26]
Shrivastava S, Bhanja CJ, Steele R, et al. Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling[J]. J Virol, 2012, 86(16):8705-8712.
[27]
Shinohara Y, Imajo K, Yoneda M, et al. Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy[J]. Biochem Biophys Res Commun, 2013, 432(2):326-332.
[28]
Kotsafti A, Farinati F, Cardin R, et al. Autophagy and apoptosis-related genes in chronic liver disease and hepatocellular carcinoma[J]. BMC Gastroenterol, 2012(12):118.
[29]
Thoen LF, Guimaraes EL, Dolle L, et al. A role for autophagy during hepatic stellate cell activation[J]. J Hepatol, 2011, 55(6):1353-1360.
[30]
Yang JD, Seol SY, Leem SH, et al. Genes associated with recurrence of hepatocellular carcinoma: integrated analysis by gene expression and methylation profiling[J]. J Korean Med Sci, 2011, 26(11):1428-1438.
[31]
Wang C, Chen K, Xia Y, et al. N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway[J]. PLoS One, 2014, 9(9):e108855.
[32]
Wang RC, Wei Y, An Z, et al. Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation[J]. Science, 2012, 338(6109):956-959.
[33]
Ge YY, Shi Q, Zheng ZY, et al. MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R[J]. Oncotarget, 2014, 5(15):6218-6228.
[34]
Takamura A, Komatsu M, Hara T, et al. Autophagy-deficient mice develop multiple liver tumors[J]. Genes Dev, 2011, 25(8):795-800.
[35]
Bareford MD, Hamed HA, Tang Y, et al. Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells[J]. Autophagy, 2011, 7(10):1261-1262.
[36]
Shi Y, Tang B, Yu PW, et al. Autophagy protects against oxaliplatin-induced cell death via ER stress and ROS in Caco-2 cells[J]. PLoS One, 2012, 7(11):e51076.
[37]
Du H, Yang W, Chen L, et al. Role of autophagy in resistance to oxaliplatin in hepatocellular carcinoma cells[J]. Oncol Rep, 2012, 27(1):143-150.
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