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中华肝脏外科手术学电子杂志

中华肝脏外科手术学电子杂志 ›› 2019, Vol. 08 ›› Issue (04) : 366 -369. doi: 10.3877/cma.j.issn.2095-3232.2019.04.020

所属专题： 文献；

临床研究

声触诊弹性成像和声触诊弹性测量检测肝脾硬度重复性研究
郑剑1, 吴曼丽2, 张敏1, 裴少华1, 王青娟1, 黄晶1, 朱利容1, 王小立2, 郑荣琴2,†()   
  1. 1. 518115　深圳市龙岗区第三人民医院超声科
    2. 510630　广州，中山大学附属第三医院超声科
  • 收稿日期:2019-06-18 出版日期:2019-08-10
  • 通信作者: 郑荣琴
  • 基金资助:
    广东省科技计划项目(2016A020215072); 广东省医学科学技术研究基金(A2016128); 深圳市科创委基金(JCYJ20170307161018414)

Repeatability of sound touch elastography and sound touch quantification in measuring liver and spleen stiffness

Jian Zheng1, Manli Wu2, Min Zhang1, Shaohua Pei1, Qingjuan Wang1, Jing Huang1, Lirong Zhu1, Xiaoli Wang2, Rongqin Zheng2,†()   

  1. 1. Department of Ultrasound, the Third People's Hospital of Shenzhen, Shenzhen 518115, China
    2. Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
  • Received:2019-06-18 Published:2019-08-10
  • Corresponding author: Rongqin Zheng
  • About author:
    Corresponding author: Zheng Rongqin, Email:
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引用本文：

郑剑, 吴曼丽, 张敏, 裴少华, 王青娟, 黄晶, 朱利容, 王小立, 郑荣琴. 声触诊弹性成像和声触诊弹性测量检测肝脾硬度重复性研究[J]. 中华肝脏外科手术学电子杂志, 2019, 08(04): 366-369.

Jian Zheng, Manli Wu, Min Zhang, Shaohua Pei, Qingjuan Wang, Jing Huang, Lirong Zhu, Xiaoli Wang, Rongqin Zheng. Repeatability of sound touch elastography and sound touch quantification in measuring liver and spleen stiffness[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2019, 08(04): 366-369.

目的

探讨声触诊弹性成像（STE）和声触诊弹性测量（STQ）检测肝、脾硬度的可重复性。

方法

选取2017年10月至2018年6月在深圳市龙岗区第三人民医院行超声检查的245例患者。患者均签署知情同意书，符合医学伦理学规定。其中男157例，女88例；年龄18～80岁，中位年龄37岁。选用两位弹性成像初学者，其中1位无超声检查经验，1位有超声检查经验，分别行肝脏、脾脏STE和STQ检查。采用组内相关系数（ICC）评价检测可重复性，比较采用Z检验。

结果

无超声经验、有超声经验初学者操作50例肝脏STE和STQ检查后ICC分别为0.912、0.971和0.922、0.963，明显高于前50例的0.667、0.825和0.698、0.834（Z=3.558，4.543和3.582，3.803；P<0.05）。对于脾脏STE和STQ，亦有类似的结果（Z=3.582，3.803和2.055，2.162；P<0.05）。操作50例后肝脏STE和STQ两位操作间ICC为0.883和0.896；脾脏STE和STQ相应为0.593和0.517。

结论

对于无论有无超声检查经验的弹性成像初学者，操作50例后可重复性明显提高，肝脏检测可重复性非常好，而脾脏可重复性有待提高。

关键词: 超声检查, 声触诊弹性成像, 声触诊弹性测量, 肝脏硬度, 脾脏硬度
Objective

To explore the repeatability of sound touch elastography (STE) and sound touch quantification (STQ) in detecting liver and spleen stiffness.

Methods

A total of 245 patients who underwent ultrasound examination in the Third People's Hospital of Shenzhen from October 2017 to June 2018 were recruited in this investigation. The informed consents of all patients were obtained and the local ethical committee approval was received. Among them, 157 patients were male and 88 female. The patients were aged from 18 to 80 years with a median age was 37 years. Two beginners were selected to perform STE and STQ of the liver and spleen. One of them had no ultrasound examination experience and the other had ultrasound examination experience. The repeatability of STE and STQ were assessed by interclass correlation coefficient (ICC) and statistically compared by Z test.

Results

The ICC of liver STE after examining 50 patientsby the beginner without ultrasound experience and the beginner with ultrasound experience were 0.912, 0.971 and the STQ were 0.922, 0.963 , respectively, significantly higher than 0.667, 0.825 and 0.698, 0.834 in the first 50 patients (Z=3.558, 4.543 and 3.582, 3.803; P<0.05). Similar results were obtained for the STE and STQ of spleen (Z=3.582, 3.803 and 2.055, 2.162; P<0.05). The ICC of STE and STQ of liver between two beginners were 0.883 and 0.896 after examination of 50 cases, and were 0.593 and 0.517 for spleen STE and STQ.

Conclusions

For the beginners of elastography with or without ultrasound examination experience, the repeatability of STE and STQ can be significantly improved after 50 cases' examination. The repeatability of liver STE and STQ is extremely high, whereas that of STE and STQ of spleen should be improved.

Key words: Ultrasonography, Sound touch elastography, Sound touch quantify, Liver stiffness, Spleen stiffness
图1 STE技术测量肝脏硬度的操作者间一致性Bland-Altman散点图
图2 STQ技术测量肝脏硬度的操作者间一致性Bland-Altman散点图
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