自身免疫性胰腺炎和胰腺导管腺癌鉴别的策略与思考

doi:10.3877/cma.j.issn.2095-3232.2024.02.001

自身免疫性胰腺炎（AIP）是一种特殊类型的胰腺炎，通常表现为无痛性梗阻性黄疸、轻度腹痛或急性胰腺炎。临床中常与胰腺导管腺癌（PDAC）相混淆，而其治疗和预后截然不同，术前明确鉴别诊断较为困难。本文将从临床表现、影像学、血清学、组织病理学等多方面阐述二者的区别，并对一些难题进行相应探讨。

关键词: 自身免疫性胰腺炎, 胰腺导管腺癌, 鉴别诊断

Autoimmune pancreatitis (AIP) is a special type of pancreatitis, which primarily manifests as painless obstructive jaundice, mild abdominal pain or acute pancreatitis. In clinical practice, it is constantly misdiagnosed with pancreatic ductal adenocarcinoma (PDAC), whereas treatment and prognosis of these two conditions are completely different. Prior to surgery, it is difficult to make a definite differential diagnosis. In this article, the differences between them were illustrated from clinical manifestations, imaging, serological and histopathological characteristics, and relevant challenging problems were discussed accordingly.

Key words: Autoimmune pancreatitis, Pancreatic ductal adenocarcinoma, Differential diagnosis

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Strategy and thinking of differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma

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Strategy and thinking of differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma