Abstract:
Objective To investigate the clinical application value of fast track surgery (FTS) in the perioperative period of laparoscopic cholecystectomy (LC).
Methods Randomized control trials (RCT) literatures related to the application of FTS in LC up to December 2016 were searched by computer from PubMed, OVID, Elsevier Sciencedirect, Cochrane Library, Embase, CNKI, China Biology Medicine Disc (CBM) and Wanfang database. The quality of the included literatures was evaluated according to the literature quality assessment method recommended by Cochrane Handbook. Relevant data including surgical status, postoperative status, length of hospital stay and hospitalization expense were extracted. Heterogenous studies were analyzed using random effect model, and homogenous studies were analyzed using fixed effect model.
Results A total of 4 454 patients in 19 RCT literatures were included in this study. Among them, 2 228 cases were assigned in the FTS group and 2 226 in the control group. Meta-analysis indicated that, the operation time, first postoperative off-bed time, first postoperative anal exhaust time and length of hospital stay in the FTS group were significantly shorter than those in the control group, and the hospitalization expense was significantly less than that in the control group (MD=-0.94, -9.59, -19.46, -2.11, -1 462.92; P<0.05).
Conclusions Application of FTS in the perioperative period of LC can significantly shorten the operation time, accelerate the postoperative recovery of the patients and reduce the hospitalization expense.
Key words:
Fast track surgery,
Cholecystectomy, laparoscopic,
Perioperative care,
Meta-analysis,
Randomized controlled trial
Hao Liang, Zhiyong Xiong, Zhicheng Yao, Kunpeng Hu, Ruixi Li, Boxuan Zhou, Ruiyun Xu, Meihai Deng. Application of fast track surgery in perioperative period of laparoscopic cholecystectomy: a Meta-analysis[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2017, 06(04): 307-311.