To explore the feasibility of complete 3D laparoscopic pancreaticoduodenectomy(LP) in treatment of ampullary carcinoma and the advantages of 3D digestive tract reconstruction.

Clinical data of 2 patients who underwent complete 3D laparoscopic pancreaticoduodenectomy in the First Affiliated Hospital of Shantou University Medical College between June and December 2016 were analyzed retrospectively. Case 1, female, 61 years old, was admitted for "yellow skin and sclera for 10 d", with TB 208 μmol/L and DB 107 μmol/L. MRCP and CT indicated ampullary tumor. Case 2, female, 62 years old, was admitted for "yellow skin and sclera for 6 d", with TB 83 μmol/L and DB 45 μmol/L. MRCP indicated a ampullary tumor. Both patients were diagnosed as periampullary carcinoma before operation. The informed consents of both patients were obtained and the local ethical committee approval was received. LP and digestive tract reconstruction were conducted by using 3D laparoscopic display system.

For case 1, the operation time was 495 min, the intraoperative blood loss was 150 ml, and no blood transfusion was conducted and postoperative pathological examination indicated duodenal periampullary adenocarcinoma. For case 2, the operation time was 445 min, the intraoperative blood loss was 120 ml, and no blood transfusion was conducted. Postoperative pathological examination indicated duodenal periampullary elevated adenocarcinoma. Both patients recovered well after operation and no tumor recurrence or metastasis was observed during 8-10 months follow-up.

It is safe and feasible to conduct complete 3D LP. 3D laparoscopic system can restore 3D vision and depth perception, which complies with the stereoscopic viewing mode of human physiology and effectively reduces the difficulty of digestive tract reconstruction.