Analysis of clinical characteristics of non-parasitic hepatic cysts and influencing factors for therapies

doi:10.3877/cma.j.issn.2095-3232.2021.03.017

Abstract

Abstract:

Objective

To investigate the clinical characteristics, treatments and influencing factors for the therapies of non-parasitic hepatic cysts.

Methods

Clinical data of 591 patients with non-parasitic hepatic cysts admitted to the First Affiliated Hospital of Xi'an Jiaotong University from January 2008 to April 2020 were retrospectively analyzed. The informed consents of all patients were obtained and the local ethical committee approval was received. Demographic data and clinical characteristics including age, sex, cyst size, cyst location and treatments were recorded. The influencing factors of treatments were analyzed by multivariate Logistic regression analysis.

Results

Among them, the proportion of male patients was 39.4%(233/591) and 60.6%(358/591) for the female counterparts, all aged from 50 to 70 years with a median age of 61 years. 194 patients were diagnosed with single hepatic cyst and 397 cases with multiple hepatic cysts. The proportion of patients presenting with clinical symptoms was 56.5%(334/591). The main symptoms included abdominal pain and distension. 494 patients received treatments, including 57 cases of ultrasound-guided hepatic cyst aspiration, 369 cases of laparoscopic hepatic cyst fenestration and drainage and 68 cases of open hepatic cyst fenestration and drainage. The cyst diameter of ≥8 cm was an independent influencing factor for the therapeutic effect (OR=5.471, 95%CI: 3.347-8.942; P<0.05).

Conclusions

Non-parasitic hepatic cysts are more prevalent in middle-aged and elderly women, and patients are mainly with multiple lesions. Fenestration and drainage is the primary treatment. Active treatment is recommended for the hepatic cyst with a diameter of ≥8 cm.

Key words: Hepatic cyst, Laparoscopes, Fenestration, Drainage

Feng Ma, Wenyu Feng, Xufeng Zhang, Yiping Mou, Xuemin Liu, Yu Li, Xiaogang Zhang, Zheng Wu, Bo Wang, Rongqian Wu, Liang Yu, Qiang Li, Yi Lyu. Analysis of clinical characteristics of non-parasitic hepatic cysts and influencing factors for therapies[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2021, 10(03): 314-317.

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References 19

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参数		总体	男性	女性	统计值	P值
年龄（岁，±s）		61±11	62±10	60±12	t=7.704	0.016
囊肿直径（cm，±s）		9±4	9±4	10±4	t=-2.292	0.022
囊肿位置（例）					χ²=7.385	0.025
	肝左叶	138	44	94
	肝右叶	259	99	160
	肝左右叶	194	90	104
囊肿数目					χ²=7.704	0.006
	单发	194	61	133
	多发	397	172	225
有临床症状（例）		334	117	217	χ²=6.212	0.013
术前合并症（例）		53	17	36	χ²=1.317	0.303

参数		总体	男性	女性	统计值	P值
年龄（岁，±s）		61±11	62±10	60±12	t=7.704	0.016
囊肿直径（cm，±s）		9±4	9±4	10±4	t=-2.292	0.022
囊肿位置（例）					χ²=7.385	0.025
	肝左叶	138	44	94
	肝右叶	259	99	160
	肝左右叶	194	90	104
囊肿数目					χ²=7.704	0.006
	单发	194	61	133
	多发	397	172	225
有临床症状（例）		334	117	217	χ²=6.212	0.013
术前合并症（例）		53	17	36	χ²=1.317	0.303

参数		干预治疗	非干预治疗	统计值	P值
年龄（岁，±s）		61±14	61±11	t=0.123	0.902
性别（例）				χ²=3.961	0.053
	男	186	47
	女	308	50
囊肿直径（cm，±s）		10±4	6±5	t=8.249	<0.001
临床症状（例）				χ²=1.347	0.264
	有	274	60
	无	220	37
单发囊肿（例）				χ²=2.867	0.098
	是	155	39
	否	339	58
囊肿位置（例）
	肝左叶	126	12	χ²=9.875	0.007
	肝右叶	216	43
	左右叶	152	42
合并症				χ²=2.067	0.102
	有	48	5
	无	446	92

参数		干预治疗	非干预治疗	统计值	P值
年龄（岁，±s）		61±14	61±11	t=0.123	0.902
性别（例）				χ²=3.961	0.053
	男	186	47
	女	308	50
囊肿直径（cm，±s）		10±4	6±5	t=8.249	<0.001
临床症状（例）				χ²=1.347	0.264
	有	274	60
	无	220	37
单发囊肿（例）				χ²=2.867	0.098
	是	155	39
	否	339	58
囊肿位置（例）
	肝左叶	126	12	χ²=9.875	0.007
	肝右叶	216	43
	左右叶	152	42
合并症				χ²=2.067	0.102
	有	48	5
	无	446	92

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