To evaluate the safety and efficacy of three-dimensional visualization technology in laparoscopic resection of huge liver tumors.

Clinical data of 50 patients who underwent huge liver tumor resection in No. 900 Hospital from July 2016 to June 2021 were retrospectively analyzed. Among them, 19 patients were male and 31 female, aged from 38 to 65 years, with a median age of 45 years. The informed consents of all patients were obtained and the local ethical committee approval was received. The tumor diameter was ranged from 10 to 17 cm, with a median diameter of 13 cm. 23 patients were diagnosed with benign tumors and 27 cases of malignant tumors. According to different surgical methods, they were divided into two groups. In the combination group, 24 cases underwent three-dimensional visualization technology combined with laparoscopic resection. In the control group, 26 cases were treated with open resection of huge liver tumors. Intraoperative and postoperative conditions of patients betweentwo groups were compared by t test or Chi-square test. Survival analysis was performed by Kaplan-Meier analysis and Log-rank test.

All patients in two groups successfully completed the surgery, and no conversion to open surgery was reported in the combination group. In the combination group, the median C-reactive protein level at postoperative 1 d was 26(18, 72) mg/L, significantly lower than 57(44, 81) mg/L in the control group (Z=-2.700, P<0.05). At postoperative 1 d, the average time to first flatus, postoperative ambulation time and the length of postoperative hospital stay were (2.6±0.8), (3.1±1.3) and (13±4) d, significantly shorter than (3.1±1.1), (4.4±1.6) and (16±6) d in the control group (t= -2.180, -3.137, -2.062; P<0.05). The incidence of postoperative complications in the combination group was 25% (6/24) and 42% (11/26) in the control group, with no statistical significance between two groups (χ²=1.666, P>0.05). The postoperative 1-, 3- and 5-year overall survival and disease-free survival rates in the combination group were 78.8%, 52.5%, 26.3% and 57.1%, 28.6%, 0, and 70.6%, 36.4%, 12.1% and 51.3%, 22.0%, 0 in the control group, with no statistical significance between two groups (χ²=0.292, 0.764; P>0.05).

Three-dimensional visualization technology can be utilized to deliver accurate preoperative evaluation for patients undergoing laparoscopic resection of huge liver tumors, and to guide accurate intraoperative operation, thus mitigating inflammatory reactions and accelerating postoperative rehabilitation.