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Chinese Journal of Hepatic Surgery(Electronic Edition) ›› 2025, Vol. 14 ›› Issue (05): 789-794. doi: 10.3877/cma.j.issn.2095-3232.2025.05.020

• Review • Previous Articles     Next Articles

Research progress in radiotherapy for lung metastasis of hepatocellular carcinoma

Xueyin Ding1,2, Juxian Sun2, Jie Shi2, Shuqun Cheng,1,2()   

  1. 1 Department of Cancer Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
    2 Department Ⅵ of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, the Third Affiliated Hospital of Naval Medical University, Shanghai 200438, China
  • Received:2025-05-07 Online:2025-10-10 Published:2025-09-25
  • Contact: Shuqun Cheng

Abstract:

Hepatocellular carcinoma (HCC) is one of the most common solid malignant tumors worldwide. Lung is the most common metastatic site of HCC. Although early diagnosis and treatment can improve clinical prognosis of HCC. However, a majority of HCC patients have been diagnosed with distant metastasis upon admission, especially lung metastasis. Therefore, the treatment of lung metastasis of HCC has gradually become a research hotspot. With the development of radiotherapy, multiple novel types of radiotherapy have been developed for lung metastasis of HCC, which provides more possibilities for enhancing efficacy. In this article, recent research progresses, including prognostic factors, therapeutic effect and application of the latest techniques, in radiotherapy for lung metastasis of HCC were reviewed and discussed from the perspectives of internal, external and combined radiotherapy, respectively.

Key words: Carcinoma, hepatocellular, Lung metastasis, Radiation therapy

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