To investigate the donor-related risk factors for biliary complications after liver transplantation (LT) from organ donation by citizens after death.

Clinical data of 110 donors who donated the organs after death and undernent LT in the Third Affiliated Hospital of Sun Yat-sen University between July 2012 and December 2015 were retrospectively analyzed. There were 91 males and 19 females, aged (29±12) years old on average. The primary disease were severe brain trauma (n=72), cerebral vascular accident (n=32) and cerebral nervous disease (n=6). The informed consents of the donors' relatives were obtained and the local ethical committee approval was received. The incidence of biliary complications after LT in the recipients was observed, and the relationship between the incidence and the clinical indexes of the donors was analyzed. The influencing factors for biliary complications after LT were analyzed using logistic regression analysis.

The incidence of biliary complications after LT in the recipients was 15.5%(17/110), including 8 cases of biliary anastomotic stricture, 6 of non-anastomotic stricture, 2 of biliary leakage and 1 of biliary stone. Multivariate logistic regression analysis revealed the warm ischemia time was the independent influencing factor for biliary complications after LT from organ donation (OR=2.104, 95%CI: 1.495-2.961; P<0.05).

Postoperative biliary complication is still the major challenge for LT from organ donation. Shortening the warm ischemia time as possible plays a pivotal role in guaranteeing high quality of donor organ and reducing the incidence of postoperative biliary complications.