To investigate the feasibility and efficacy of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and simultaneous radical resection of colon cancer in treating patients with colorectal liver metastases.

Clinical data of 1 patient with sigmoid colon cancer and liver metastases treated in the First Affiliated Hospital of Lanzhou University in August 2015 were analyzed retrospectively. The patient was male, 51 years old. The informed consent was obtained and the local ethical committee approval was received. In the first stage of operation, laparoscopic radical resection of colon cancer, ligation of right branch of portal vein, and in situ liver splitting were performed. In the second stage, laparoscopic extended right hemihepatectomy and local resection of liver metastases were performed. The perioperative parameters of this patient were analyzed.

Operations of two stages were completed successfully under total laparoscope. The operation time of first stage was 350 min, and intraoperative bleeding was 450 ml. Three weeks after operation, the remnant liver volume to total liver volume was 39%, then the second stage operation was performed. Liver function of the patient recovered well after operation.

For patients with colorectal liver metastases, two stage operations of ALPPS can be performed safely under laparoscope. ALPPS and simultaneous resection of primary colon cancer is reasonable and safe.