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Chinese Journal of Hepatic Surgery(Electronic Edition) ›› 2021, Vol. 10 ›› Issue (01): 33-37. doi: 10.3877/cma.j.issn.2095-3232.2021.01.008

Special Issue:

• Clinical Research • Previous Articles     Next Articles

Comparison of safety and efficacy between laparoscopic and open left hepatectomy in treatment of hepatolithiasis: a Meta-analysis

Chao Niu1, Bo Li1, Wendi Jin1, Chunxiao Wang1, Xiaogang Li1,()   

  1. 1. Department I of General Surgery, the Second People's Hospital of Yunnan Province, Kunming 650021, China
  • Received:2020-09-20 Online:2021-02-10 Published:2021-02-10
  • Contact: Xiaogang Li

Abstract:

Objective

To systematically compare the safety and efficacy between laparoscopic left hepatectomy (LLH) and open left hepatectomy (OLH) in the treatment of hepatolithiasis.

Methods

Literature related to left hepatectomy for hepatolithiasis between January 2010 to January 2020 were retrieved in database of PubMed, EMBASE, CNKI, Wanfang and VIP. Clinical parameters including operation time, intraoperative blood loss, length of hospital stay, time to initial anal exhaust, time to out-of-bed activity and postoperative complications were collected. Meta-analysis was conducted by using Review Manager 5.3 software.

Results

A total of 11 eligible articles were included, all of which were studies of clinical randomized controlled trials. Among 773 patients, 387 cases were allocated in the LLH group and 386 casesin the OLH group. Meta-analysis demonstrated that compared with OLH, LLH could significantly shorten the length of hospital stay, time to initial anal exhaust and time to out-of-bed activity (MD=-3.27, -0.98, -1.20; P<0.05), and remarkably lowered the incidence of postoperative complications and incisional infection (OR=0.39, 0.31; P<0.05).

Conclusions

Compared with OLH, LLH has multiple advantages of shorter length of hospital stay, less postoperative complications and faster postoperative recovery, which can accelerate postoperative rehabilitation of patients.

Key words: Hepatolithiasis, Hepatectomy, Laparoscopes, Meta-analysis

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