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Chinese Journal of Hepatic Surgery(Electronic Edition) ›› 2022, Vol. 11 ›› Issue (06): 625-628. doi: 10.3877/cma.j.issn.2095-3232.2022.06.018

• Clinical Research • Previous Articles     Next Articles

Diagnostic consistency between contrast-enhanced ultrasound and MRI for biological activity of hepatic alveolar echinococcosis

Xu Deng1, Junwei Han1, Jingjing Wang1, Lingqiang Zhang1, Xiaozhou Yang1, Zhao Li1, Haijiu Wang1, Haining Fan1, Mingde Lyu2, Cairang Yangdan1,()   

  1. 1. Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Qinghai University, Key Laboratory of Echinococcosis Research in Qinghai Province, Xining 810000, China
    2. Department of Ultrasound, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
  • Received:2022-08-08 Online:2022-12-10 Published:2022-11-21
  • Contact: Cairang Yangdan

Abstract:

Objective

To assess the diagnostic consistency between contrast-enhanced ultrasound (CEUS) and MRI for hepatic alveolar echinococcosis (HAE).

Methods

47 patients with HAE admitted to the Affiliated Hospital of Qinghai University from October 2019 to December 2020 were recruited. The informed consents of all patients were obtained and the local ethical committee approval was received. Among them, 17 patients were male and 30 female, aged (36±2) years on average. All patients received CEUS and MRI within 1 week. The imaging features were analyzed to assess the biological activity of lesions. The consistency between the enhancement pattern by CEUS and vesicle-like structure by MRI in the diagnosis of biological activity of HAE was analyzed by Kappa test.

Results

77 lesions were detected from 47 cases by CEUS. 62 lesions revealed peripheral enhancement including 19 lesions of hyperenhancement, 15 isoenhancement and 28 hypoenhancement. According to the revised MRI Kodama classification,1 lesion was classified as type 1, 20 lesions were type 2, 37 lesions were type 3, 17 lesions were type 4 and 2 lesions were types 5. 53 lesions with vesicle-like structures possessed biological activity were observed by MRI, and 62 lesions were detected by CEUS. The consistency between two imaging tools was high (κ=0.696, P<0.001).

Conclusions

CEUS and MRI yield high diagnostic consistency for the biological activity of HAE lesions. Compared with MRI, CEUS is more convenient, easy to operate and economical, and it can be utilized to effectively evaluate the biological activity of HAE lesions and monitor the changes of HAE during follow-up.

Key words: Echinococcosis, hepatic, Ultrasonography, interventional, Magnetic resonance imaging, Biological activity

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