Chinese Clinical Practice Guidelines on Split Liver Transplantation in Children

doi:10.3877/cma.j.issn.2095-3232.2024.05.001

Abstract

Abstract:

Liver transplantation is an effective treatment for end-stage liver disease in children, and its clinical efficacy has been validated. Split liver transplantation can effectively expand the donor liver pool for children. Split liver transplantation for children has specific clinical characteristics and principles. Establishing technical operation specifications for pediatric split liver transplantation plays a significant role in improving clinical efficacy. In this article, clinical practice guidelines on pediatric split liver transplantation was established in the aspect of donor and donor liver evaluation, donor-recipient matching, and ductal segmentation and reconstruction of donor liver, aiming to standardize the technical process, optimize surgical procedures, reduce the incidence of complications of split liver transplantation for children, further promoting rapid development of pediatric split liver transplantation in China.

Key words: Split liver transplantation, Children, Liver transplantation, Guideline

Chinese Society of Organ Transplantation of Chinese Medical Association, Surgery Group of Chinese Society of Surgery of Chinese Medical Association, Transplantation Group of Chinese Society of Surgery of Chinese Medical Association, South China Alliance of Split Liver Transplantation. Chinese Clinical Practice Guidelines on Split Liver Transplantation in Children[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2024, 13(05): 593-601.

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URL: https://zhgzwkssxdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-3232.2024.05.001

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References 106

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指标	参考值范围
年龄	<50岁
BMI	<26 kg/m²
ICU住院时间	<5 d
升压药	血流动力学稳定或低剂量升压药
肝脏脂肪变性比例	<10%
AST/ALT	<3倍正常上限
总胆红素	<2倍正常上限
GGT	<50 U/L
血清钠	<160 mmol/L
预计冷缺血时间	<10 h

指标	参考值范围
年龄	<50岁
BMI	<26 kg/m²
ICU住院时间	<5 d
升压药	血流动力学稳定或低剂量升压药
肝脏脂肪变性比例	<10%
AST/ALT	<3倍正常上限
总胆红素	<2倍正常上限
GGT	<50 U/L
血清钠	<160 mmol/L
预计冷缺血时间	<10 h

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