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Chinese Journal of Hepatic Surgery(Electronic Edition) ›› 2024, Vol. 13 ›› Issue (05): 705-709. doi: 10.3877/cma.j.issn.2095-3232.2024.05.020

• Clinical Research • Previous Articles    

Establishment of standardized management regimen for endoscopic tissue glue injection for gastric varices based on endoscopic operation detail recording system

Yanping Liang1, Shiyun Lie1, Yisui Wang1, Xiaoying Wu2, Ying Lin1,()   

  1. 1. Department of Gastroenterology, the Third Affiliated Hospital ofSun Yat-sen University, Guangzhou 510630, China
    2. Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510002, China
  • Received:2024-05-27 Online:2024-10-10 Published:2024-09-19
  • Contact: Ying Lin

Abstract:

Objective

To establish a standardized management regimen for endoscopic cyanoacrylate injection (ECI) for gastric varices based on the endoscopic operation detail recording system, and to evaluate the application value of this regimen in the evaluation of ECI efficacy.

Methods

110 patients with gastric varices due to cirrhosis and portal hypertension who underwent ECI in the Third Affiliated Hospital ofSun Yat-sen University from October 2019 to October 2021 were enrolled. Among them, 88 patients were male and 22 female, aged (53±11) years on average. An endoscopic operation detail recording system was established. A standardized management regimen for liver cirrhosis ECI was established including daily training, preoperative preparation, intraoperative operation highlights, intraoperative emergency plan and postoperative follow-up, etc. At postoperative 1 month, gastroscopy was performed to evaluate the therapeutic effect.

Results

In this study, an endoscopic operation detail recording system was established, which could not only record operation details such as the amount of cyanoacrylate, injection site, injection points, injection time, length of injection needle, diameter of injection needle and compression time after injection, but also included quality indexes such as one-time success rate, incidence rate of needle blockage, cyanoacrylate leakage, cyanoacrylate sticking and physician satisfaction degree, etc. The one-time success rate of ECI was 98.2% (108/110). The incidence of intraoperative adverse events was 14.5% (16/110), including 7 cases of bleeding, 3 cases of cyanoacrylate leakage and 2 cases of cyanoacrylate sticking, 2 cases of cyanoacrylate leakage combined with glue sticking, 1 case of bleeding combined with cyanoacrylate sticking, and 1 case of bleeding combined with cyanoacrylate leakage and sticking after needle extraction. The incidence of early postoperative re-bleeding was 3.6% (4/110), and no delayed bleeding occurred. 82 cases were followed up at postoperative 1 month, and the follow-up rate was 74.5% (82/110). The total effective rate of ECI was 87% (72/82). The effective rate was 59% (49/82) and the significantly effective rate was 28% (23/82).

Conclusions

For liver cirrhosis patients undergoing ECI, the standardized management regimen established by endoscopic operation detail recording system can record the operation details, standardize the operation process and digitally analyze the causes of failure, thereby ensuring high success rate of endoscopic treatment operation.

Key words: Endoscopic operation details recording system, Standard operating process, Gastric varices, Tissue adhesive injection, Efficacy evaluation

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