| ［1］ |
Sung H，Ferlay J，Siegel RL，et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries［J］. CA Cancer J Clin，2021，71（3）:209-249.
|
| ［2］ |
Cao W，Chen HD，Yu YW，et al. Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020［J］. Chin Med J，2021，134（7）:783-791.
|
| ［3］ |
中华人民共和国国家卫生健康委员会医政司. 原发性肝癌诊疗指南（2024年版）［J/OL］. 中华肝脏外科手术学电子杂志，2024，13（4）:407-449.
|
| ［4］ |
Anderson NL，Anderson NG. Proteome and proteomics: new technologies，new concepts，and new words［J］. Electrophoresis，1998，19（11）:1853-1861.
|
| ［5］ |
Nogueira Silva Lima MT，Howsam M，Delayre-Orthez C，et al.Glycated bovine serum albumin for use in feeding trials with animal models - in vitro methodology and characterization of a glycated substrate for modifying feed pellets［J］. Food Chem，2023，428:136815.
|
| ［6］ |
King RM，Gounis MJ，Schmidt EJ，et al. Molecular magnetic resonance imaging of aneurysmal inflammation using a redox active iron complex［J］. Invest Radiol，2023，58（9）:656-662.
|
| ［7］ |
Liu T，Joshu CE，Lu J，et al. External validation of genetically predicted protein biomarkers for pancreatic cancer risk using aptamer-based plasma levels: a prospective analysis in the Atherosclerosis Risk in Communities Study［J］. Int J Cancer，2023，153（6）:1201-1216.
|
| ［8］ |
Kaur G，Poljak A，Ali SA，et al. Extending the depth of human plasma proteome coverage using simple fractionation techniques［J］.J Proteome Res，2021，20（2）:1261-1279.
|
| ［9］ |
Zhang Y，Ying X，Zhao Q，et al. Identification of protein expression changes in hepatocellular carcinoma through iTRAQ［J］. Dis Markers，2020: 2632716.
|
| ［10］ |
Nouri-Vaskeh M，Alizadeh L，Hajiasgharzadeh K，et al. The role of HSP90 molecular chaperones in hepatocellular carcinoma［J］. J Cell Physiol，2020，235（12）:9110-9120.
|
| ［11］ |
Wang Z，Zhang Z，Zhang Y，et al. MXenes-Au NPs modified electrochemical biosensor for multiple exosome surface proteins analysis［J］. Talanta，2023，265:124848.
|
| ［12］ |
Regin M，Essahib W，Demtschenko A，et al. Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1［J］. Hum Reprod，2023，38（8）:1484-1498.
|
| ［13］ |
Bangarh R，Khatana C，Kaur S，et al. Aberrant protein glycosylation:implications on diagnosis and Immunotherapy［J］. Biotechnol Adv，2023，66:108149.
|
| ［14］ |
Hochberg JD，Wirth DM，Pokorski JK. Surface-modified melt coextruded nanofibers enhance blood clotting in vitro［J］. Macromol Biosci，2022，22（12）:e2200292.
|
| ［15］ |
Gidwani K，Kekki H，Terävä J，et al. Nanoparticle-aided glycovariant assays to bridge biomarker performance and ctDNA results［J］. Mol Aspects Med，2020，72:100831.
|
| ［16］ |
Yin H，Lin Z，Nie S，et al. Mass-selected site-specific corefucosylation of ceruloplasmin in alcohol-related hepatocellular carcinoma［J］. J Proteome Res，2014，13（6）:2887-2896.
|
| ［17］ |
Liang W，Cong B，Lai W，et al. An electrochemiluminescence resonance energy transfer biosensor based on Luminol-LDH and CuS@Pt for detection of alpha-fetoprotein［J］. Talanta，2023，261:124669.
|
| ［18］ |
Wei F，Su Y，Quan Y，et al. Anticoagulants enhance molecular and cellular immunotherapy of cancer by improving tumor microcirculation structure and function and redistributing tumor infiltrates［J］. Clin Cancer Res，2023，29（13）:2525-2539.
|
| ［19］ |
Terkelsen T，Russo F，Gromov P，et al. Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer，tumor grade，and immune infiltration［J］. Breast Cancer Res，2020，22（1）:73.
|
| ［20］ |
Wang L，Wu X，Ruan Y，et al. Exosome-transmitted hsa_circ_0012634 suppresses pancreatic ductal adenocarcinoma progression through regulating miR-147b/HIPK2 axis［J］. Cancer Biol Ther，2023，24（1）:2218514.
|
| ［21］ |
Matas-Nadal C，Bech-Serra JJ，Guasch-Vallés M，et al. Evaluation of tumor interstitial fluid-extraction methods for proteome analysis:comparison of biopsy elution versus centrifugation［J］. J Proteome Res，2020，19（7）:2598-2605.
|
| ［22］ |
Hajji M，Hamdi M，Sellimi S，et al. Structural characterization，antioxidant and antibacterial activities of a novel polysaccharide from Periploca laevigata root barks［J］. Carbohydr Polym，2019，206:380-388.
|
| ［23］ |
Zhang J，Hao N，Liu W，et al. In-depth proteomic analysis of tissue interstitial fluid for hepatocellular carcinoma serum biomarker discovery［J］. Br J Cancer，2017，117（11）:1676-1684.
|
| ［24］ |
Sun W，Xing B，Guo L，et al. Quantitative proteomics analysis of tissue interstitial fluid for identification of novel serum candidate diagnostic marker for hepatocellular carcinoma［J］. Sci Rep，2016，6:26499.
|
| ［25］ |
Dani S，Kumar R，Sharma H，et al. Integrated experimental and theoretical studies on structural and magnetic properties of thin films of double perovskite ruthenates: Ba2DyRuO6 & Sr2DyRuO6［J］.Phys Chem Chem Phys，2023，25（31）:20863-20870.
|
| ［26］ |
Dmowski M，Makiela-Dzbenska K，Sharma S，et al. Impairment of the non-catalytic subunit Dpb2 of DNA Pol ɛ results in increased involvement of Pol δ on the leading strand［J］. DNA Repair，2023，129:103541.
|
| ［27］ |
Wang LH，Cao B，Li YL，et al. Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins family［J］. BMC Cancer，2023，23（1）:674.
|
| ［28］ |
Zhao CC，Yu WW，Qi YJ，et al. Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells［J］. Anticancer Drugs，2020，31（3）:223-230.
|
| ［29］ |
Sheng D，Zhao B，Zhu W，et al. Scutellaria barbata D.Don （SBD）extracts suppressed tumor growth，metastasis and angiogenesis in Prostate cancer via PI3K/Akt pathway［J］. BMC Complement Med Ther，2022，22（1）:120.
|
| ［30］ |
Xing X，Yuan H，Liu H，et al. Quantitative secretome analysis reveals clinical values of carbonic anhydrase Ⅱ in hepatocellular carcinoma［J］. Genomics Proteomics Bioinformatics，2021，19（1）:94-107.
|
| ［31］ |
Seay TW，Suo Z. Roles of extracellular vesicles on the progression and metastasis of hepatocellular carcinoma［J］. Cells，2023，12（14）:1879.
|
| ［32］ |
Uzzaman A，Zhang X，Qiao Z，et al. Discovery of small extracellular vesicle proteins from human serum for liver cirrhosis and liver cancer［J］. Biochimie，2020，177:132-141.
|
| ［33］ |
Alic L，Binder CJ，Papac-Milicevic N. The OSE complotype and its clinical potential［J］. Front Immunol，2022，13:1010893.
|
| ［34］ |
Sahebi R，Langari H，Fathinezhad Z，et al. Exosomes: new insights into cancer mechanisms［J］. J Cell Biochem，2020，121（1）:7-16.
|
| ［35］ |
Thuya WL，Kong LR，Syn NL，et al. FAM3C in circulating tumorderived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites［J］. Theranostics，2023，13（2）:621-638.
|
| ［36］ |
Whiteside TL. Evaluating tumor cell- and T cell-derived extracellular vesicles as potential biomarkers of cancer and immune cell［J］. Expert Rev Mol Diagn，2023，23（2）:109-122.
|
| ［37］ |
Feng J，Xiu Q，Huang Y，et al. Plant-derived vesicle-like nanoparticles as promising biotherapeutic tools: present and future［J］.Adv Mater，2023，35（24）:e2207826.
|
| ［38］ |
Portales AE，Miguel I，Rodriguez MJ，et al. CDK4/6 are necessary for UCP1-mediated thermogenesis of white adipose tissue［J］. Life Sci，2023，322:121652.
|
| ［39］ |
Nimitrungtawee N，Inmutto N，Chattipakorn SC，et al. Extracellular vesicles as a new hope for diagnosis and therapeutic intervention for hepatocellular carcinoma［J］. Cancer Med，2021，10（23）:8253-8271.
|
| ［40］ |
de Paepe J，Garcia Gragera D，Arnau Jimenez C，et al. Continuous cultivation of microalgae yields high nutrient recovery from nitrified urine with limited supplementation［J］. J Environ Manage，2023，345:118500.
|
| ［41］ |
Sun Y，Guan B，Liu X，et al. Screening for urinary markers predicting hematopoietic stem cell injury induced by busulfan using genetically diverse mice［J］. Animal Model Exp Med，2023，6（2）:146-154.
|
| ［42］ |
Kiernan E，Surapaneni A，Zhou L，et al. Alterations in the circulating proteome associated with albuminuria［J］. J Am Soc Nephrol，2023，34（6）:1078-1089.
|
| ［43］ |
Sirirungreung A，Hansen J，Ritz B，et al. Association between medically diagnosed postnatal infection and childhood cancers:a matched case-control study in Denmark，1978 to 2016［J］. Int J Cancer，2023，153（5）:994-1002.
|
| ［44］ |
Zhao Y，Li Y，Liu W，et al. Identification of noninvasive diagnostic biomarkers for hepatocellular carcinoma by urinary proteomics［J］. J Proteomics，2020，225:103780.
|
| ［45］ |
Ramos-Campoy O，Lladó A，Bosch B，et al. Differential gene expression in sporadic and genetic forms of Alzheimer's disease and frontotemporal dementia in brain tissue and lymphoblastoid cell lines［J］. Mol Neurobiol，2022，59（10）:6411-6428.
|
| ［46］ |
Lian X，Zhang W，He-Yang J，et al. Human milk oligosaccharide disialyllacto-n-tetraose protects human intestinal epithelium integrity and permeability against mast cell chymase-induced disruption by stabilizing ZO-1/FAK/P38 pathway of intestinal epithelial cell［J］.Immunopharmacol Immunotoxicol，2023，45（4）:409-418.
|
| ［47］ |
Ikeda C，Haga H，Makino N，et al. Utility of Claudin-3 in extracellular vesicles from human bile as biomarkers of cholangiocarcinoma［J］.Sci Rep，2021，11（1）:1195.
|
| ［48］ |
Swain AK，Pandey P，Sera R，et al. Single-cell transcriptome analysis identifies novel biomarkers involved in major liver cancer subtypes［J］. Funct Integr Genomics，2023，23（3）:235.
|
| ［49］ |
Shimi G，Sohrab G，Pourvali K，et al. Correlation of low levels of α-1 antitrypsin and elevation of neutrophil to lymphocyte ratio with higher mortality in severe COVID-19 patients［J］. Mediat Inflamm，2021: 5555619.
|
| ［50］ |
Boroumand M，Olianas A，Cabras T，et al. Saliva，a bodily fluid with recognized and potential diagnostic applications［J］. J Sep Sci，2021，44（19）:3677-3690.
|
| ［51］ |
Silumbwe A，San Sebastian M，Zulu JM，et al. The role of principled engagement in public health policymaking: the case of Zambia's prolonged efforts to develop a comprehensive tobacco control policy［J］. Glob Health Action，2023，16（1）:2212959.
|
| ［52］ |
Ford CE，Werner B，Hacker NF，et al. The untapped potential of ascites in ovarian cancer research and treatment［J］. Br J Cancer，2020，123（1）:9-16.
|
| ［53］ |
Hsi TC，Ong KL，Sepers JJ，et al. Systemic coagulopathy promotes host lethality in a new Drosophila tumor model［J］. Curr Biol，2023，33（14）:3002-3010，e6.
|
| ［54］ |
Yu P，Chen W，Ge L，et al. Logic gate-driven dual-index balanced visualization strategy for tumor metastasis diagnosis［J］. Biosens Bioelectron，2023，237:115556.
|
| ［55］ |
Kitamura F，Miyata T，Uemura N，et al. Proteomic analysis of malignant ascites from patients with pancreatic ductal adenocarcinoma［J］. Anticancer Res，2021，41（6）:2895-2900.
|
| ［56］ |
Yoshizawa Y，Nakao T，Tsuritani K，et al. The importance of specific citrullinated clusterin and vimentin found in a multi-coloured beadbased citrulline-peptide array system in rheumatoid arthritis［J］. Clin Exp Rheumatol，2022，40（5）:936-944.
|