Recent advances in surgical strategies for hepatic alveolar echinococcosis

doi:10.3877/cma.j.issn.2095-3232.2025.03.022

Abstract

Abstract:

Hepatic alveolar echinococcosis （HAE） is a zoonotic parasitic disease caused by E.multilocularis infection， which is globally distributed. In China， it is mainly prevalent in the western agricultural and pastoral areas such as Xinjiang， Qinghai and Xizang， which seriously endangers the health of people of all ethnic groups and affects economic development. The liver is the main target organ of HAE. The lesions constantly grow in an infiltrative pattern， manifested with biological behavior resembling malignant tumors， also known as “worm cancer”. In the late stage， it can invade the hepatic inflow and outflow tract vessels and adjacent tissues and organs， even leading to liver failure in severe cases. At present， radical surgical resection combined with albendazole drug therapy is the first choice. The development of the disease is relatively hidden. Upon admission， most patients are diagnosed with large lesions and the invasion of the main vessels， which brings challenges to radical surgery. At present， with the development of precise medicine and individualized diagnosis and treatment concepts， surgical treatment methods have been significantly improved. In this article， the latest progress in surgical treatment of HAE was reviewed， aiming to provide theoretical basis for the formulation of diagnosis and treatment strategies for HAE.

Key words: Hepatic alveolar echinococcosis, Surgical treatment, Radical hepatectomy, Liver transplantation, Progress of treatment

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