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Chinese Journal of Hepatic Surgery(Electronic Edition) ›› 2026, Vol. 15 ›› Issue (02): 257-260. doi: 10.3877/cma.j.issn.2095-3232.2026.02.017

• Review • Previous Articles    

Application of ICG fluorescence image in anatomical liver resection of liver tumors

Shuhao Zheng, Weiwei Li, Wenkang Yuan, Chao Zhang, Chong Zhang()   

  1. Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
  • Received:2025-07-24 Online:2026-04-10 Published:2026-04-02
  • Contact: Chong Zhang

Abstract:

Liver tumors are primarily treated with comprehensive therapy based on liver resection. The advantages of anatomical liver resection (ALR) in the treatment of liver tumors have been widely recognized in this field. However, it is challenging for the surgeons to precisely determine the scope of liver resection. ICG fluorescence imaging technology has been adopted for a long period of time and it is relatively safe, which can identify liver tumors during intraoperative imaging and enhance the precision of ALR. However, ICG has limited penetration and high false positive rate, and its clinical efficacy remains controversial. In this article, the development, application, imaging mechanism of ICG fluorescence laparoscopy in liver tumors, and its defects and limitations were reviewed, aiming to provide reference for the application of ICG fluorescence imaging technology in LAR in the future.

Key words: Indocyanine green, Hepatectomy, Anatomical liver resection, Carcinoma, hepatocellular, Fluorescence molecular imaging

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