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Chinese Journal of Hepatic Surgery(Electronic Edition) ›› 2026, Vol. 15 ›› Issue (03): 326-336. doi: 10.3877/cma.j.issn.2095-3232.2026.03.006

• Frontiers and Debates • Previous Articles    

Multi-mode diagnostic strategies for liver cancer

Yachao Shi1, Liumu Wei1, Xiaoge Dong1, Haining Fan2,3, Lichao Hou2,3, Kaihao Du1, Zhanjin Wang1, Weiwei Xue1, Haigang Liu1, Zhan Wang2,3,4,()   

  1. 1 Clinical Medical College of Qinghai University, Xining 810000, China
    2 Department of Hepatobiliary and Pancreatic Surgery, Qinghai University Affiliated Hospital, Xining 810000, China
    3 Qinghai Province Key Laboratory of Hydatid Disease Research, Xining 810000, China
    4 Department of Medical Engineering and Translational Application, Qinghai University Affiliated Hospital, Xining 810000, China
  • Received:2025-10-15 Online:2026-06-10 Published:2026-06-05
  • Contact: Zhan Wang

Abstract:

Liver cancer is one of the main malignant tumors worldwide. Early diagnosis and treatment are of significance for improving the survival rate of patients. In recent years, medical imaging, tumor markers and artificial intelligence (AI) technologies have played a critical role in the diagnosis and management of liver cancer. Imaging technologies, such as ultrasound, CT, MRI and radionuclide imaging, have been widely applied in the screening, diagnosis, grading and treatment evaluation of liver cancer. Tumor markers, such as AFP, AFP-L3 and PIVKA-Ⅱ, are important tools in the diagnosis of liver cancer, which are known as "triple detections of liver cancer". AI technologies, especially deep learning and neural network model, can effectively analyze medical imaging data and assist physicians to make more accurate diagnosis. Integrated application of these technologies is expected to further enhance early diagnosis rate and the overall survival of liver cancer patients.

Key words: Primary liver cancer, Carcinoma,hepatocellular, Imaging examinations, Tumor markers, Artificial intelligence

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