To evaluate the safety and efficacy of single-port laparoscopic cholecystectomy (LC) combined with laparoscopic common bile duct exploration (LCBDE) and biliary stent implantation and primary suture in the treatment of cholecystolithiasis complicated with common bile duct stones.

Clinical data of 18 patients with cholecystolithiasis and common bile duct stones who underwent single-port LC combined with LCBDE and biliary stent implantation and primary suture in Chengdu Second People's Hospital from November 2024 to March 2025 were retrospectively analyzed. The informed consents of all patients were obtained and the local ethical committee approval was received. Among them, 4 patients were male and 14 female, aged (54±21) years. 2 cases were complicated with pancreatitis and 1 case complicated with diabetes. Body mass index (BMI) was ranged from 19.3 to 33.2 kg/m², with a median of 23.5 kg/m². The operation time, intraoperative blood loss, postoperative complications, the length of hospital stay and follow-up outcomes were observed. To evaluate the learning curve of surgical technologies, 18 patients were divided into group A (n=9) and B (n=9) according to the date of surgery. The operation time between two groups was compared by t-test.

All 18 patients successfully completed the surgery without conversion to open surgery. The operation time was (131±31) min. Intraoperative blood loss was (24±8) ml. The diameter of common bile duct was 10 (8-23) mm. The maximum diameter of the stones was 6 (3-21) mm. The number of stones was 2 (1-12). Abdominal drainage catheter was placed in 11 out of 18 patients. The operation time in group A and B was (143±31) and (119±28) min, with no statistical significance (t=723, P=0.104). All patients were recovered well after surgery, and began to receive liquid diet at postoperative 1-2 d. The time to first flatus was 2-3 d after surgery. No perioperative death, incisional infection, biliary stricture, residual stone and bile leakage occurred. The length of hospital stay was 9 (6-10) d. During follow-up at postoperative 1 month showed that all stents fell off spontaneously. No residual stones, bile duct stenosis or other complications were found. All patients restored normal work and life.

Single-port LC combined with LCBDE and biliary stent implantation and primary suture is a safe and effective minimally invasive surgical procedure for patients with cholecystolithiasis and common bile duct stones, which can not only treat cholecystolithiasis and common bile duct stones, but also has multiple advantages of mild trauma, rapid recovery and favorable cosmetic effect.