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中华肝脏外科手术学电子杂志 ›› 2015, Vol. 04 ›› Issue (03): 154 -156. doi: 10.3877/cma.j.issn.2095-3232.2015.03.005

所属专题: 文献

临床研究

腹腔镜脾切除+贲门周围血管离断术治疗肝硬化门静脉高压症
钟新华1, 刘媛2, 刘波3, 胡昆鹏3,()   
  1. 1. 510530 广州,中山大学附属第三医院岭南医院门诊办公室
    2. 510530 广州,中山大学附属第三医院岭南医院护理部
    3. 510530 广州,中山大学附属第三医院岭南医院普通外科
  • 收稿日期:2015-02-02 出版日期:2015-06-10
  • 通信作者: 胡昆鹏
  • 基金资助:
    广东省自然科学基金(S2013010015552)

Laparoscopic splenectomy combined with pericardial devascularization in the treatment of cirrhosis-induced portal hypertension

Xinhua Zhong1, Yuan Liu2, Bo Liu3, Kunpeng Hu3,()   

  1. 1. Outpatient Office, Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510530, China
    2. Nursing Department, Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510530, China
    3. Department of General Surgery, Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510530, China
  • Received:2015-02-02 Published:2015-06-10
  • Corresponding author: Kunpeng Hu
  • About author:
    Corresponding author: Hu Kunpeng, Email:
目的

探讨腹腔镜脾切除+贲门周围血管离断术(断流术)在治疗肝硬化门静脉高压症中的安全性和应用价值。

方法

回顾性研究2011年11月至2013年11月在中山大学附属第三医院岭南医院接受腹腔镜断流术的32例肝硬化门静脉高压症患者临床资料。其中男26例,女6例;年龄40~69岁,中位年龄53岁。所有患者均签署知情同意书,符合医学伦理学规定。患者在气管插管静脉复合麻醉下行腹腔镜断流术。术前1周戒烟、戒酒,行呼吸功能训练和床上排便训练。术后严密监测生命体征,观察引流量等情况。

结果

全部患者腹腔镜断流术均成功完成。平均手术时间为(110±15)min,术中出血量(200±52)ml,住院时间(7±2)d。术后3个月内定期行凝血功能和门静脉彩色多普勒超声检查,术后发生门静脉血栓7例,根据血小板和血栓情况给予调整抗血小板和抗凝治疗后治愈。围手术期无发生死亡、大出血、消化道瘘及感染。

结论

腹腔镜断流术是治疗肝硬化门静脉高压症的一种安全、有效方法,严密的围手术期处理可以为手术安全提供保障。

Objective

To investigate the safety and application value of laparoscopic splenectomy combined with pericardial devascularization (devascularization) in the treatment of cirrhosis-induced portal hypertension.

Methods

Clinical data of 32 patients with cirrhosis and portal hypertension undergoing laparoscopic devascularization in Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University from November 2011 to November 2013 were retrospectively studied. Among the 32 patients, 26 were males and 6 were females with the age ranging from 40 to 69 years old and the median of 53 years old. The informed consents of all patients were obtained and the local ethical committee approval had been received. The patients received laparoscopic devascularization under intratracheal intubation anesthesia combined with intravenous anesthesia. One week before surgery, the patients were instructed to quit smoking and drinking, and received respiratory function training and in-bed toilet training. Vital signs were closely monitored and drainage volume was observed after surgery.

Results

All patients received larparoscopic devascularization successfully, with the average operation time of (110±15) min, intraoperative blood loss of (200±52) ml and length of hospital stay of (7±2) d. The blood coagulation and color Doppler ultrasound of portal vein were regularly followed up within 3 months after surgery. Seven cases suffered portal vein thrombosis after surgery and recovered after adjusting the anti-platelet and anti-coagulation therapy according to the situation of platelets and thrombus. No death, massive hemorrhage, digestive tract fistula and infection occurred during perioperative period.

Conclusions

Laparoscopic devascularization in the treatment of cirrhosis-induced portal hypertension is safe and effective. The rigorous perioperative management guarantees the safety of surgery.

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