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中华肝脏外科手术学电子杂志 ›› 2023, Vol. 12 ›› Issue (03) : 352 -355. doi: 10.3877/cma.j.issn.2095-3232.2023.03.021

所属专题: 综述

综述

胰十二指肠切除术后胰瘘发生的危险因素及预防
李扬1, 史亚波1, 涂建华1, 黄长文2,()   
  1. 1. 330006 南昌大学医学院
    2. 511518 广州医科大学附属第六医院(清远市人民医院)肝胆胰脾外科
  • 收稿日期:2023-01-28 出版日期:2023-06-10
  • 通信作者: 黄长文

Risk factors and prophylaxis for pancreatic fistula after pancreaticoduodenectomy

Yang Li1, Yabo Shi1, Jianhua Tu1   

  • Received:2023-01-28 Published:2023-06-10
引用本文:

李扬, 史亚波, 涂建华, 黄长文. 胰十二指肠切除术后胰瘘发生的危险因素及预防[J]. 中华肝脏外科手术学电子杂志, 2023, 12(03): 352-355.

Yang Li, Yabo Shi, Jianhua Tu. Risk factors and prophylaxis for pancreatic fistula after pancreaticoduodenectomy[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(03): 352-355.

胰十二指肠切除术(pancreaticoduodenectomy,PD)是治疗胰腺恶性肿瘤或壶腹周围良恶性病变的主要手术方式,也是普通外科中难度最大、解剖部位最为复杂、风险最高的手术之一,因其切除器官多,操作复杂,堪称外科手术中的"珠穆朗玛峰"。随着外科手术技术的提高及围手术期管理水平的不断发展,PD术后死亡率已有明显的下降,约在5%以下[1]。然而,PD术后并发症发生率一直居高不下,仍高达30%~50%[2]。术后胰瘘(postoperative pancreatic fistula,POPF)作为PD术后最严重的并发症之一,一旦发生可能导致腹腔内感染、出血、腹腔脓肿,并在某些情况下导致休克甚至死亡,因此,对POPF危险因素的预测及防治至关重要。

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