巨脾是门静脉高压症等疾病常见的合并症，其导致的脾功能亢进症和凝血功能异常等会对患者健康造成诸多影响，目前巨脾的治疗包括介入治疗和手术治疗，其中脾切除术是最为有效的治疗方案。近年来巨脾切除术多在腹腔镜下完成，尽管已有多种手术入路和围手术期处理方案用于提高巨脾切除手术的安全性，但仍易引起腹腔出血、周围脏器损伤等并发症。对于伴有重度脾功能亢进症的巨脾患者先行介入治疗再序贯手术治疗可能是较好的治疗选择。

Splenomegaly is a common complication of portal hypertension and other diseases, leading to hypersplenism and coagulation abnormality, which will exert multiple effects on patients' health. At present, interventional therapy and surgery are the main treatment options for splenomegaly, among which splenectomy is the most effective procedure. In recent years, splenectomy is primarily performed under laparoscopy. Although multiple surgical approaches and perioperative management measures have been adopted to improve the safety of splenectomy, it is still likely to cause complications, such as abdominal bleeding and peripheral organ damage, etc. Interventional therapy followed by sequential surgery may be a favorable treatment option for splenomegaly patients complicated with severe hypersplenism.