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中华肝脏外科手术学电子杂志 doi: 10.3877/cma.j.issn.2095-3232.2024982

指南与共识

肝移植术后缺血性胆道病变诊断与治疗中国实践指南
中华医学会器官移植学分会   
  • 收稿日期:2024-07-16
  • 基金资助:
    国家自然科学基金面上项目(82270689); 中山大学附属第三医院重大人才培育计划(P02452); 广州市科技计划市校(院)企业联合资助项目(2024A03J0273); 广州地区临床高新、重大、特色技术(2023P-GX05)

Chinese practice guidelines for diagnosis and treatment of ischemic-type biliary lesion after liver transplantation

Branch of Organ Transplantation of Chinese Medical Association   

  • Received:2024-07-16
  • About author:
    The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
引用本文:

中华医学会器官移植学分会. 肝移植术后缺血性胆道病变诊断与治疗中国实践指南[J]. 中华肝脏外科手术学电子杂志, doi: 10.3877/cma.j.issn.2095-3232.2024982.

Branch of Organ Transplantation of Chinese Medical Association. Chinese practice guidelines for diagnosis and treatment of ischemic-type biliary lesion after liver transplantation[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), doi: 10.3877/cma.j.issn.2095-3232.2024982.

我国肝脏移植历经多年的探索发展,其技术及预后已得到显著提高,术后并发症发生率也随之降低,但缺血性胆道病变仍是一个不容忽视的问题。中山大学附属第三医院于2015年制订并发表《中国大陆地区肝移植后缺血性胆道病变诊断及治疗专家共识》,现结合现阶段情况及文献报道进行更新并形成指南。本指南从缺血性胆道病变的定义、发生率、发病机制、诊断、高危因素的预防以及治疗等方面进行详细阐述,旨在为肝移植术后缺血性胆道病变的诊断与治疗提供标准化、规范化的指导,以降低再移植率和病死率,提高肝移植受者的整体生存质量。

Over the years of exploration and development, the surgical techniques and prognosis of liver transplantation in China have been significantly improved, resulting in a notable decrease in the prevalence of postoperative complications. However, ischemic-type biliary lesion remain a non-negligible issue. The Third AffiliatedHospital of Sun Yat-sen University formulated and published the "Expert Consensus on the Diagnosis and Treatment ofIschemic-Type Biliary Lesions after Liver Transplantation in Mainland China" in 2015, which has now been updated into aguideline based on current conditions and literature reports. This guideline elaborates in detail on the definition, incidence,pathogenesis, diagnosis, prevention of high-risk factors, and treatment of ischemic-type biliary lesion, aiming to providestandardized and normative guidance for the diagnosis and treatment of ischemic-type biliary lesion after liver transplantation, thereby reducing the rate of re-transplantation and fatality, and to improve the overall quality of life of liver transplant recipients.

表1 牛津大学证据分级与推荐意见强度分级标准
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