Application of peripheral blood cfDNA liquid biopsy in diagnosis and treatment of hepatic echinococcosis

doi:10.3877/cma.j.issn.2095-3232.2024.03.022

Abstract

Abstract:

Circulating cell-free DNA (cfDNA) is a nucleic acid fragment mainly existing in blood and other body fluids, including nuclear DNA and mitochondrial DNA. As a "liquid biopsy" technique, cfDNA has high application value in the diagnosis, prognosis and clinical efficacy monitoring of hepatic echinococcosis, which is expected to become a new-generation diagnosis and treatment approach for hepatic echinococcosis.

Key words: cfDNA, Echinococcosis, hepatic, Liquid biopsy, High-throughput sequencing (NGS), Diagnosis, Efficacy monitoring

Zhiyi Yang, Chengjun Zhao, Xinyuan Hu, Baimeng Pan, Qiuyu Zhang, Wanqian Zhang, Rui Cao, Lingqiang Zhang. Application of peripheral blood cfDNA liquid biopsy in diagnosis and treatment of hepatic echinococcosis[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2024, 13(03): 389-393.

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