Abstract:

Benign gallbladder disease is one of the most widely distributed diseases in China with the largest number of patients. Benign gallbladder diseases can be pathologically divided into intragallbladder lesions and diffuse or localized thickening of gallbladder wall. Except for cholesterol polyps，most benign gallbladder diseases have the risk of malignant transformation. Scientific preoperative evaluation，intraoperative selection of appropriate surgical approaches，proper postoperative management of gallbladder samples and establishment of standardized diagnosis and treatment process for benign gallbladder diseases can effectively reduce misdiagnosis and inappropriate treatment of gallbladder cancer.

Key words: Benign gallbladder disease, Gallbladder cancer, Incidental gallbladder cancer, Gallbladder adenomyomatosis, Preoperative evaluation, Surgical approach, Specimen handling