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中华肝脏外科手术学电子杂志 ›› 2018, Vol. 07 ›› Issue (06) : 460 -464. doi: 10.3877/cma.j.issn.2095-3232.2018.06.007

所属专题: 文献

临床研究

经肝右静脉离断并重建入路肝尾状叶肿瘤切除术
杨雪1, 石磊1, 李起1, 郭健1, 吕毅1, 耿智敏1,()   
  1. 1. 710061 西安交通大学第一附属医院肝胆外科
  • 收稿日期:2018-09-07 出版日期:2018-12-10
  • 通信作者: 耿智敏
  • 基金资助:
    西安交通大学2016年临床新技术(XJLS-2016-361)

Resection of caudate lobe tumor via devascularization and reconstruction of right hepatic vein

Xue Yang1, Lei Shi1, Qi Li1, Jian Guo1, Yi Lyu1, Zhimin Geng1,()   

  1. 1. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China
  • Received:2018-09-07 Published:2018-12-10
  • Corresponding author: Zhimin Geng
  • About author:
    Corresponding author: Geng Zhimin, Email:
引用本文:

杨雪, 石磊, 李起, 郭健, 吕毅, 耿智敏. 经肝右静脉离断并重建入路肝尾状叶肿瘤切除术[J]. 中华肝脏外科手术学电子杂志, 2018, 07(06): 460-464.

Xue Yang, Lei Shi, Qi Li, Jian Guo, Yi Lyu, Zhimin Geng. Resection of caudate lobe tumor via devascularization and reconstruction of right hepatic vein[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2018, 07(06): 460-464.

目的

探讨经肝右静脉离断并重建入路肝尾状叶肿瘤切除术安全性和疗效。

方法

回顾性分析2017年11月西安交通大学第一附属医院1例肝尾状叶肿瘤切除术患者临床资料。患者女,54岁,术前诊断为肝尾状叶肝细胞癌。患者签署患者知情同意书,符合医学伦理学规定。采用新创的经肝右静脉离断并重建入路法实施肝尾状叶肿瘤切除术,优先处理肝短静脉,离断肝右静脉后切除尾状叶肿瘤,再重建肝右静脉。

结果

手术顺利,术中阻断右半肝血流及肝下下腔静脉20 min,全肝血流阻断1次,时间15 min,术中出血量800 ml,输红细胞4 U。术后常规给予抗感染、抑酸、降低门静脉压力、护肝、营养支持治疗。术后7 d复查上腹部CT示肝右叶近肝门处斑片状低密度影,门静脉不宽,肝内胆管无扩张,胆囊窝少量积气积液。病理学检查结果示肝块状型中分化肝细胞癌伴局部囊性变。术后15 d恢复顺利出院。

结论

与其他尾状叶手术方式相比,经肝右静脉离断并重建入路肝尾状叶肿瘤切除术创伤更小、出血量更少,是一种新的尾状叶切除入路,适用于累及腔静脉及尾状突的尾状叶肿瘤切除。

Objective

To evaluate the safety and clinical efficacy of resection of caudate lobe tumor via devascularization and reconstruction of right hepatic vein.

Methods

Clinical data of a patient who underwent resection of caudate lobe tumor in the First Affiliated Hospital of Xi'an Jiaotong University in November 2017 were retrospectively analyzed. The patient was female, 54-year-old, was diagnosed with hepatocellular carcinoma in the liver caudate lobe before operation. The informed consent of the patient was obtained and the local ethical committee approval was received. Resection of caudate lobe tumor was performed via a new approach, devascularization and reconstruction of the right hepatic vein. The short hepatic vein was treated preferentially. Devascularization of the right hepatic vein was performed, followed by resection of caudate lobe tumors and subsequently the right hepatic vein was reconstructed.

Results

The operation was successfully accomplished. Blood flow of the right lobe and the inferior hepatic vena cava was excluded for 20 min. Total hepatic flow was occluded once for 15 min. The intraoperative blood loss was 800 ml, and 4 U of red blood cell transfusion was performed. Postoperative treatments anti-infection, acid suppression, lowering portal vein pressure, liver protection and nutritional support were routinely delivered. CT scan of the upper abdomen at postoperative 7 d indicated patchy low-density shadows in the right lobe near the hepatic porta, no expansion of the portal vein and intrahepatic bile duct, and a slight pneumatosis and hydrops in the gallbladder fossa. Pathological examination showed a bulky moderately-differentiated hepatocellular carcinoma combined with local cystic lesions. The patient recovered well and discharged at postoperative 15 d.

Conclusions

Compared with the conventional caudate lobectomy, devascularization and reconstruction of the right hepatic vein is a novel approach for caudate lobectomy with slighter trauma and less bleeding, which is suitable for the resection of caudate lobe tumor involving the vena cava and caudate process.

图1 肝尾状叶肿瘤患者术前CT及CT血管造影检查
图2 肝尾状叶肿瘤患者术中情况
[1]
王许安, 刘颖斌, 全志伟, 等. 临床解剖结构在肝尾状叶切除术中的重要性[J]. 中国实用外科杂志, 2014, 34(8):720-723.
[2]
徐礼治, 汪继勇, 汪益民. 肝尾状叶切除术的研究进展[J]. 肝胆胰外科杂志, 2015, 27(1):82-83.
[3]
Ho KM, Han HS, Yoon YS, et al. Laparoscopic total caudate lobectomy for hepatocellular carcinoma[J]. J Laparoendosc Adv Surg Tech A, 2017, 27(10):1074-1078.
[4]
王宏光, 纪文斌, 赵之明, 等. 达芬奇机器人手术系统在精准肝切除中的应用[J]. 中华消化外科杂志, 2010, 9(2):97-100.
[5]
Cheung TT. Technical notes on pure laparoscopic isolated caudate lobectomy for patient with liver cancer[J]. Transl Gastroenterol Hepatol, 2016(1):56.
[6]
Shindoh J, Nishioka Y, Hashimoto M. Bilateral anatomic resection of the ventral parts of the paramedian sectors of the liver with total caudate lobectomy for deeply/centrally located liver tumors: a new technique maximizing both oncological and surgical safety[J].J Hepatobiliary Pancreat Sci, 2017, 24(12):E10-16.
[7]
Chaib E, Ribeiro MA Jr, Silva Fde S, et al. Caudate lobectomy: tumor location, topographic classification, and technique using right- and left-sided approaches to the liver[J]. Am J Surg, 2008, 196(2):245-251.
[8]
Peng SY, Liu YB, Wang JW, et al. Retrograde resection of caudate lobe of liver[J]. J Am Coll Surg, 2008, 206(6):1232-1238.
[9]
耿小平. 肝尾状叶肿瘤切除的技术难点与对策[J]. 中华消化外科杂志, 2013, 12(1):30-33.
[10]
Araki K, Fuks D, Nomi T, et al. Feasibility of laparoscopic liver resection for caudate lobe: technical strategy and comparative analysis with anteroinferior and posterosuperior segments[J]. Surg Endosc, 2016, 30(10):4300-4306.
[11]
戴朝六. 肝脏巨大尾状叶肿瘤切除术应注意的几个问题[J/CD]. 中华普通外科学文献(电子版), 2010, 4(1):3-6.
[12]
余德才, 吴星宇. 以尾状叶为中心解剖性肝切除的临床定义与意义[J/CD]. 中华腔镜外科杂志电子版, 2017, 10(3):131-135.
[13]
Jin Y, Wang L, Yu YQ, et al. Anatomic isolated caudate lobectomy: is it possible to establish a standard surgical flow?[J]. World J Gastroenterol, 2017, 23(41):7433-7439.
[14]
Kim JK, Hwang HK, Park JS, et al. Left hemihepatectomy and caudate lobectomy and complete extrahepatic bile duct resection using transduodenal approach for hilar cholangiocarcinoma arsing from biliary papillomatosis[J]. J Surg Oncol, 2008, 98(2):139-142.
[15]
De Lu C, Huang J, Wu SD, et al. Total hilar en bloc resection with left hemihepatectomy and caudate lobectomy: a novel approach for treatment of left-sided perihilar cholangiocarcinoma (with video)[J]. J Gastrointest Surg, 2017, 21(11):1906-1914.
[16]
Hiroshima Y, Matsuo K, Kawaguchi D, et al. Modified liver hanging maneuver for en-bloc right-sided hepatectomy combined with total caudate lobectomy for colon-cancer liver metastasis and hepatocellular carcinoma[J]. Anticancer Res, 2016, 36(4):1729-1735.
[17]
Perini MV, Coelho FF, Kruger JA, et al. Extended right hepatectomy with caudate lobe resection using the hilar "en bloc" resection technique with a modified hanging maneuver[J]. J Surg Oncol, 2016, 113(4):427-431.
[18]
汪珍光, 傅思源, 林川, 等. 经前入路肝尾状叶全切除术治疗累及腔静脉旁部肝肿瘤的临床疗效[J]. 中华消化外科杂志, 2017, 16(2):195-200.
[19]
Ochiai T, Ishii H, Toma A, et al. Modified high dorsal procedure for performing isolated anatomic total caudate lobectomy (with video)[J]. World J Surg Oncol, 2016(14):132.
[20]
苏正, 刘波, 刘建平, 等. 前入路肝切除术在原发性肝癌手术中的应用价值[J/CD]. 中华肝脏外科手术学电子杂志, 2016, 5(1):16-20.
[21]
汪珍光, 傅思源, 周伟平, 等. 逆行右半肝联合全尾状叶肿瘤切除术[J]. 中华消化外科杂志, 2013, 12(9):655-658.
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