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中华肝脏外科手术学电子杂志 ›› 2023, Vol. 12 ›› Issue (03) : 253 -257. doi: 10.3877/cma.j.issn.2095-3232.2023.03.001

所属专题: 述评与论坛

述评

基于Kupffer细胞特异性摄取的术中超声造影在肝脏外科中的应用
许静涌1, 宋京海1,()   
  1. 1. 100730 国家老年医学中心 中国医学科学院老年医学研究院北京医院普通外科(肝胆胰外科)
  • 收稿日期:2023-01-30 出版日期:2023-06-10
  • 通信作者: 宋京海
  • 基金资助:
    中央高水平医院临床科研业务费(BJ-2022-128)

Application of intraoperative contrast-enhanced ultrasonography based on specific uptaking of Kupffer cell in hepatic surgery

Jingyong Xu1, Jinghai Song1()   

  • Received:2023-01-30 Published:2023-06-10
  • Corresponding author: Jinghai Song
引用本文:

许静涌, 宋京海. 基于Kupffer细胞特异性摄取的术中超声造影在肝脏外科中的应用[J]. 中华肝脏外科手术学电子杂志, 2023, 12(03): 253-257.

Jingyong Xu, Jinghai Song. Application of intraoperative contrast-enhanced ultrasonography based on specific uptaking of Kupffer cell in hepatic surgery[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(03): 253-257.

超声技术是肝脏疾病诊治不可或缺的基本技术,包括术前、术中及术后应用。术前应用主要为肝脏疾病的诊断,特别是肿瘤的诊断、鉴别诊断及定位,此外还包括对肝弥漫性病变,如肝硬化、脂肪肝等的严重程度评估,术后超声主要用于治疗后病灶及残余肝脏的随访。术前和术后超声多为超声医学科医师的工作,而术中超声(intraoperative ultrasound,IOUS)则是肝脏外科领域的内容,在肝脏外科应用的历史超过40年[1]。特别是近年来,随着精准肝切除和微创外科理念的兴起与推广,熟练掌握IOUS技术成为肝脏外科医师孜孜不倦的探索与追求。

[1]
Makuuchi M, Hasegawa H, Yamazaki S. Intraoperative ultrasonic examination for hepatectomy[J]. Ultrasound Med Biol, 1983(Suppl 2): 493-497.
[2]
Nicolau C, Vilana R, Catalá V, et al. Importance of evaluating all vascular phases on contrast-enhanced sonography in the differentiation of benign from malignant focal liver lesions[J]. AJR Am J Roentgenol, 2006, 186(1):158-167.
[3]
Li C, Liu Y, Xu J, et al. Contrast-enhanced intraoperative ultrasonography with Kupffer phase may change treatment strategy of metastatic liver tumors-a single-centre prospective study[J]. Ther Clin Risk Manag, 2021(17):789-796.
[4]
李晨, 刘媛, 许静涌, 等. 基于Kupffer细胞特异性摄取的超声造影在肝脏肿瘤性病变诊断中的应用价值[J]. 中华肝胆外科杂志, 2020, 26(12):907-911.
[5]
Yanagisawa K, Moriyasu F, Miyahara T, et al. Phagocytosis of ultrasound contrast agent microbubbles by Kupffer cells[J]. Ultrasound Med Biol, 2007, 33(2):318-325.
[6]
Sontum PC. Physicochemical characteristics of Sonazoid, a new contrast agent for ultrasound imaging[J]. Ultrasound Med Biol, 2008, 34(5):824-833.
[7]
Li P, Hoppmann S, Du P, et al. Pharmacokinetics of perfluorobutane after intra-venous bolus injection of Sonazoid in healthy Chinese volunteers[J]. Ultrasound Med Biol, 2017, 43(5):1031-1039.
[8]
Kudo M, Ueshima K, Osaki Y, et al. B-mode ultrasonography versus contrast-enhanced ultrasonography for surveillance of hepatocellular carcinoma: a prospective multicenter randomized controlled trial[J]. Liver Cancer, 2019, 8(4):271-280.
[9]
Lv K, Zhai H, Jiang Y, et al. Prospective assessment of diagnostic efficacy and safety of SonazoidTM and SonoVue® ultrasound contrast agents in patients with focal liver lesions[J]. Abdom Radiol, 2021, 46(10):4647-4659.
[10]
Takahashi H, Sugimoto K, Kamiyama N, et al. Noninvasive diagnosis of hepatocellular carcinoma on Sonazoid-enhanced US: value of the Kupffer phase[J]. Diagnostics, 2022, 12(1):141.
[11]
Sugimoto K, Kakegawa T, Takahashi H, et al. Usefulness of modified CEUS LI-RADS for the diagnosis of hepatocellular carcinoma using Sonazoid[J]. Diagnostics, 2020, 10(10):828.
[12]
Hatanaka K, Kudo M, Minami Y, et al. Sonazoid-enhanced ultrasonography for diagnosis of hepatic malignancies: comparison with contrast-enhanced CT[J]. Oncology, 2008, 75 Suppl 1:42-47.
[13]
Kim YY, Min JH, Hwang JA, et al. Second-line Sonazoid-enhanced ultrasonography for Liver Imaging Reporting and Data System category 3 and 4 on gadoxetate-enhanced magnetic resonance imaging[J]. Ultrasonography, 2022, 41(3):519-529.
[14]
Kawada N, Ohkawa K, Tanaka S, et al. Improved diagnosis of well-differentiated hepatocellular carcinoma with gadolinium ethoxybenzyl diethylene triaminepentaacetic acid-enhanced magnetic resonance imaging and Sonazoid contrast-enhanced ultrasonography[J]. Hepatol Res, 2010, 40(9):930-936.
[15]
Iwamoto T, Imai Y, Kogita S, et al. Comparison of contrast-enhanced ultrasound and Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced MRI for the diagnosis of macroscopic type of hepatocellular carcinoma[J]. Dig Dis, 2016, 34(6):679-686.
[16]
Arita J, Takahashi M, Hata S, et al. Usefulness of contrast-enhanced intraoperative ultrasound using Sonazoid in patients with hepatocellular carcinoma[J]. Ann Surg, 2011, 254(6):992-999.
[17]
Fergadi MP, Magouliotis DE, Vlychou M, et al. A meta-analysis evaluating contrast-enhanced intraoperative ultrasound (CE-IOUS) in the context of surgery for colorectal liver metastases[J]. Abdom Radiol, 2021, 46(9):4178-4188.
[18]
Itabashi T, Sasaki A, Otsuka K, et al. potential value of sonazoid-enhanced intraoperative laparoscopic ultrasonography for liver assessment during laparoscopy-assisted colectomy[J]. Surg Today, 2014, 44(4):696-701.
[19]
Kudo M. Breakthrough imaging in hepatocellular carcinoma[J]. Liver Cancer, 2016, 5(1):47-54.
[20]
Uchiyama K, Ueno M, Ozawa S, et al. Combined intraoperative use of contrast-enhanced ultrasonography imaging using a sonazoid and fluorescence navigation system with indocyanine green during anatomical hepatectomy[J]. Langenbecks Arch Surg, 2011, 396(7):1101-1107.
[21]
李晨, 许静涌, 刘媛, 等. Sonazoid超声造影与MRI融合引导消融肝微小转移1例[J]. 中华肝胆外科杂志, 2022, 28(3):228-229.
[22]
Maruyama H, Sekimoto T, Yokosuka O. Role of contrast-enhanced ultrasonography with Sonazoid for hepatocellular carcinoma: evidence from a 10-year experience[J]. J Gastroenterol, 2016, 51(5):421-433.
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