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中华肝脏外科手术学电子杂志 ›› 2024, Vol. 13 ›› Issue (05) : 634 -639. doi: 10.3877/cma.j.issn.2095-3232.2024.05.008

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新辅助治疗时代胰腺癌淋巴结清扫研究进展
周倜1, 吴嘉2, 韩方2, 徐林伟2, 张宇华1,()   
  1. 1. 311100 浙江省杭州市临平区第一人民医院普通外科
    2. 310022 杭州,浙江省肿瘤医院肝胆胰外科
  • 收稿日期:2024-06-19 出版日期:2024-10-10
  • 通信作者: 张宇华

Research progress in lymph node dissection for pancreatic cancer in the era of neoadjuvant therapy

Ti Zhou1, Jia Wu2, Fang Han2, Linwei Xu2, Yuhua Zhang1,()   

  1. 1. Department of General Surgery, the First People's Hospital of Linping District, Hangzhou 311100, China
    2. Department of Hepatobiliary and Pancreatic Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China
  • Received:2024-06-19 Published:2024-10-10
  • Corresponding author: Yuhua Zhang
引用本文:

周倜, 吴嘉, 韩方, 徐林伟, 张宇华. 新辅助治疗时代胰腺癌淋巴结清扫研究进展[J]. 中华肝脏外科手术学电子杂志, 2024, 13(05): 634-639.

Ti Zhou, Jia Wu, Fang Han, Linwei Xu, Yuhua Zhang. Research progress in lymph node dissection for pancreatic cancer in the era of neoadjuvant therapy[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2024, 13(05): 634-639.

胰腺癌恶性程度高且预后极差,易发生转移。淋巴结转移是影响胰腺癌患者预后的重要因素。对于胰腺癌术中的淋巴结清扫范围及数量,国内外学者进行了诸多探索,但对胰腺癌患者的预后改善依然有效。近年来,随着肿瘤综合治疗理念的改变,新辅助治疗在胰腺癌中的应用日渐受到重视,也大大改善了患者的预后,但对于接受新辅助治疗的患者,其淋巴结清扫的数量及范围是否需要进一步优化仍存在争议,需要更多的循证医学证据予以支持并改进,从而使胰腺癌患者获得更好的治疗效果。

Pancreatic cancer is characterized with high-degree malignancy and poor prognosis, which is likely to metastasize. Lymph node metastasis is an important factor affecting clinical prognosis of pancreatic cancer patients. Scholars at home and abroad have conducted extensive studies on the range and quantity of lymph node dissection during pancreatic cancer surgery, whereas it is still effective in improving clinical prognosis of pancreatic cancer patients. In recent years, with the change of the concept of comprehensive tumor treatment, the application of neoadjuvant therapy has captivated increasing attention in pancreatic cancer, which has significantly enhanced clinical prognosis of patients. However, whether the number and range of lymph node dissection should be further optimized for patients receiving neoadjuvant therapy remains controversial, which should be supported and improved by more evidence-based medical data, thereby providing better therapeutic effect for patients with pancreatic cancer.

表1 日本胰腺协会胰周淋巴结分组
图1 胰腺癌不同术式淋巴结清扫范围
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