切换至 "中华医学电子期刊资源库"

中华肝脏外科手术学电子杂志 ›› 2025, Vol. 14 ›› Issue (05) : 673 -679. doi: 10.3877/cma.j.issn.2095-3232.2025.05.003

专家论坛

肝脏外科治疗理念的变迁与技术进步
袁文康, 张冲, 张超()   
  1. 230022 合肥,安徽医科大学第一附属医院普通外科
  • 收稿日期:2025-04-20 出版日期:2025-10-10
  • 通信作者: 张超
  • 基金资助:
    国家自然科学基金(82303475); 安徽省高等学校科学研究项目(2022AH040161)

Changes in the concept and technical progress of liver surgery

Wenkang Yuan, Chong Zhang, Chao Zhang()   

  1. Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
  • Received:2025-04-20 Published:2025-10-10
  • Corresponding author: Chao Zhang
引用本文:

袁文康, 张冲, 张超. 肝脏外科治疗理念的变迁与技术进步[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(05): 673-679.

Wenkang Yuan, Chong Zhang, Chao Zhang. Changes in the concept and technical progress of liver surgery[J/OL]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2025, 14(05): 673-679.

肝脏外科相关疾病的治疗多采用以手术治疗为主的综合疗法,肝脏外科手术难度大,往往涉及复杂的解剖及精细的血管吻合。如何减少手术出血量、提高手术安全性、简化手术操作、降低并发症和死亡率,一直是肝脏外科领域研究的焦点。随着人们生活水平的提高,对医疗质量的要求随之提升,将微创外科、精准外科、加速康复外科(ERAS)理念融入肝脏外科诊疗过程,顺应时代发展的要求。而随着科技的进步,以三维可视化技术为代表数字化技术,推动了外科手术的智能化、精准化、微创化发展。本文就近年来肝脏外科治疗理念的变迁和技术进步做一阐述。

Surgery-based comprehensive treatment is primarily adopted for liver surgery-related diseases. Liver surgery is highly challenging, which involves complex anatomy and fine vascular anastomosis. How to reduce the amount of bleeding, improve the safety of surgery, simplify surgical procedures, reduce the incidence of complications and mortality rate have been the focus of research in the field of liver surgery. With the improvement of living standards, the requirements for medical quality have been elevated accordingly. The concepts of minimally invasive surgery, precision surgery and enhanced recovery after surgery (ERAS) have been integrated into the diagnosis and treatment of liver surgery to meet the requirements in the modern era. With the progress in science and technology, digital technologies represented by three-dimensional visualization technology have accelerated the development of intelligent, precise and minimally invasive surgery. In this article, recent changes in the concept and technical progress of liver surgery were reviewed.

[1]
Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. DOI: 10.3322/caac.21660.
[2]
Niu X, Liu J, Feng Z, et al. Short-term efficacy of precise hepatectomy and traditional hepatectomy for primary liver cancer: a systematic review and meta-analysis[J]. J Gastrointest Oncol, 2021, 12(6): 3022-3032. DOI: 10.21037/jgo-21-735.
[3]
董家鸿, 叶晟. 开启精准肝胆外科的新时代[J/OL]. 中华普外科手术学杂志(电子版), 2016, 10(3): 181-184. DOI: 10.3877/cma.j.issn.1674-3946.2016.03.001.
[4]
Joliat GR, Kobayashi K, Hasegawa K, et al. Guidelines for perioperative care for liver surgery: enhanced recovery after surgery (ERAS) society recommendations 2022[J]. World J Surg, 2023, 47(1): 11-34. DOI: 10.1007/s00268-022-06732-5.
[5]
陈亚进. ERAS理念与精准微创肝切除[J]. 中华医学信息导报, 2021, 36(22): 15. DOI: 10.3760/cma.j.issn.1000-8039.2021.22.127.
[6]
Liu Y, Wang Q, Du B, et al. A meta-analysis of the three-dimensional reconstruction visualization technology for hepatectomy[J]. Asian J Surg, 2023, 46(2): 669-676. DOI: 10.1016/j.asjsur.2022.07.006.
[7]
Wang JZ, Xiong NY, Zhao LZ, et al. Review fantastic medical implications of 3D-printing in liver surgeries, liver regeneration, liver transplantation and drug hepatotoxicity testing: a review[J]. Int J Surg, 2018, 56: 1-6. DOI: 10.1016/j.ijsu.2018.06.004.
[8]
Potharazu AV, Gangemi A. Indocyanine green (ICG) fluorescence in robotic hepatobiliary surgery: a systematic review[J]. Int J Med Robot, 2023, 19(1): e2485. DOI: 10.1002/rcs.2485.
[9]
Lang H, Huber T. Virtual and augmented reality in liver surgery[J]. Ann Surg, 2020, 271(1): e8. DOI: 10.1097/SLA.0000000000003601.
[10]
Wu X, Wang D, Xiang N, et al. Augmented reality-assisted navigation system contributes to better intraoperative and short-time outcomes of laparoscopic pancreaticoduodenectomy: a retrospective cohort study[J]. Int J Surg, 2023, 109(9): 2598-2607. DOI: 10.1097/JS9.0000000000000536.
[11]
李映安, 晋云, 储心昀, 等. 混合现实技术在腹腔镜肝切除术中导航的应用[J/OL]. 中华肝脏外科手术学电子杂志, 2023, 12(4): 401-406. DOI: 10.3877/cma.j.issn.2095-3232.2023.04.008.
[12]
Reich H, McGlynn F, DeCaprio J, et al. Laparoscopic excision of benign liver lesions[J]. Obstet Gynecol, 1991, 78(5 Pt 2): 956-958.
[13]
周伟平, 孙志宏, 吴孟超, 等. 经腹腔镜肝叶切除首例报道[J]. 肝胆外科杂志, 1994, 2(2): 82.
[14]
Azagra JS, Goergen M, Gilbart E, et al. Laparoscopic anatomical (hepatic) left lateral segmentectomy-technical aspects[J]. Surg Endosc, 1996, 10(7): 758-761. DOI: 10.1007/BF00193052.
[15]
林融风, 华永飞, 陆才德. 腹腔镜肝切除中转危险因素的研究进展[J]. 中华普通外科杂志, 2020, 35(7): 590-592. DOI: 10.3760/cma.j.cn11385520191211-00733.
[16]
Buell JF, Cherqui D, Geller DA, et al. The international position on laparoscopic liver surgery: the Louisville Statement, 2008[J]. Ann Surg, 2009, 250(5): 825-830. DOI: 10.1097/sla.0b013e3181b3b2d8.
[17]
Wakabayashi G, Cherqui D, Geller DA, et al. Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in morioka[J]. Ann Surg, 2015, 261(4): 619-629. DOI: 10.1097/SLA.0000000000001184.
[18]
中华医学会外科学分会肝脏外科学组. 腹腔镜肝切除术专家共识和手术操作指南(2013版)[J]. 中华外科杂志, 2013, 51(4): 289-292. DOI: 10.3760/cma.j.issn.1673-9752.2013.03.001.
[19]
尹新民, 朱鹏, 张万广, 等. 腹腔镜肝切除术专家共识(2013版)[J]. 中国肿瘤临床, 2013, 40(6): 303-307. DOI: 10.3969/j.issn.1000-8179.2013.06.001.
[20]
Di Benedetto F, Magistri P, Di Sandro S, et al. Safety and efficacy of robotic vs open liver resection for hepatocellular carcinoma[J]. JAMA Surg, 2023, 158(1): 46-54. DOI: 10.1001/jamasurg.2022.5697.
[21]
Dai YS, Gao W, Hu HJ, et al. Laparoscopic left hepatectomy for intrahepatic cholangiocarcinoma[J]. Ann Surg Oncol, 2024, 31(5): 3059-3061. DOI: 10.1245/s10434-024-14905-w.
[22]
Fichtinger RS, Aldrighetti LA, Abu Hilal M, et al. Laparoscopic versus open hemihepatectomy: the ORANGE II PLUS multicenter randomized controlled trial[J]. J Clin Oncol, 2024, 42(15): 1799-1809. DOI: 10.1200/JCO.23.01019.
[23]
Nam YY, Hong SK, Hong SY, et al. Pure laparoscopic vs open right hepatectomy in patients with hepatocellular carcinoma: a propensity score-matched analysis[J]. J Hepatobiliary Pancreat Sci, 2023, 30(3): 293-302. DOI: 10.1002/jhbp.1232.
[24]
Nguyen KT, Gamblin TC, Geller DA. World review of laparoscopic liver resection-2, 804 patients[J]. Ann Surg, 2009, 250(5): 831-841. DOI: 10.1097/SLA.0b013e3181b0c4df.
[25]
Giulianotti PC, Coratti A, Angelini M, et al. Robotics in general surgery: personal experience in a large community hospital[J]. Arch Surg, 2003, 138(7): 777-784. DOI: 10.1001/archsurg.138.7.777.
[26]
Chong CC, Fuks D, Lee KF, et al. Propensity score-matched analysis comparing robotic and laparoscopic right and extended right hepatectomy[J]. JAMA Surg, 2022, 157(5): 436-444. DOI: 10.1001/jamasurg.2022.0161.
[27]
Hu Y, Guo K, Xu J, et al. Robotic versus laparoscopic hepatectomy for malignancy: a systematic review and meta-analysis[J]. Asian J Surg, 2021, 44(4): 615-628. DOI: 10.1016/j.asjsur.2020.12.016.
[28]
Ziogas IA, Giannis D, Esagian SM, et al. Laparoscopic versus robotic major hepatectomy: a systematic review and meta-analysis[J]. Surg Endosc, 2021, 35(2): 524-535. DOI: 10.1007/s00464-020-08008-2.
[29]
Zhang L, Yuan Q, Xu Y, et al. Comparative clinical outcomes of robot-assisted liver resection versus laparoscopic liver resection: a meta-analysis[J]. PLoS One, 2020, 15(10): e0240593. DOI: 10.1371/journal.pone.0240593.
[30]
Goh BK, Lee SY, Chan CY, et al. Early experience with robot-assisted laparoscopic hepatobiliary and pancreatic surgery in Singapore: single-institution experience with 20 consecutive patients[J]. Singapore Med J, 2018, 59(3): 133-138. DOI: 10.11622/smedj.2017092.
[31]
杨世忠, 冯晓彬, 董家鸿. 精准外科理念指导下的肝癌外科治疗[J]. 精准医学杂志, 2018, 33(3): 189-192, 196. DOI: 10.13362/j.jpmed.201803001.
[32]
Liao K, Yang K, Cao L, et al. Laparoscopic anatomical versus non-anatomical hepatectomy in the treatment of hepatocellular carcinoma: a randomised controlled trial[J]. Int J Surg, 2022, 102: 106652. DOI: 10.1016/j.ijsu.2022.106652.
[33]
Minagawa M, Mise Y, Omichi K, et al. Anatomic resection for hepatocellular carcinoma: prognostic impact assessed from recurrence treatment[J]. Ann Surg Oncol, 2022, 29(2): 913-921. DOI: 10.1245/s10434-021-10380-9.
[34]
Zhang J, Zhang P, Cao J. Safety and efficacy of precision hepatectomy in the treatment of primary liver cancer[J]. BMC Surg, 2023, 23(1): 241. DOI: 10.1186/s12893-023-02148-7.
[35]
Yao WF, Huang XK, Fu TW, et al. Precise planning based on 3D-printed dry-laboratory models can reduce perioperative complications of laparoscopic surgery for complex hepatobiliary diseases: a preoperative cohort study[J]. BMC Surg, 2024, 24(1): 148. DOI: 10.1186/s12893-024-02441-z.
[36]
曾广斌. 腹腔镜超声下左半肝切除术治疗原发性肝癌患者的临床效果[J]. 医疗装备, 2023, 36(22): 78-80. DOI: 10.3969/j.issn.1002-2376.2023.22.024.
[37]
Wang J, Xu Y, Zhang Y, et al. Safety and effectiveness of fluorescence laparoscopy in precise hepatectomy: a meta-analysis[J]. Photodiagnosis Photodyn Ther, 2023, 42: 103599. DOI: 10.1016/j.pdpdt.2023.103599.
[38]
Nazir A, Cheema MN, Sheng B, et al. SPST-CNN: spatial pyramid based searching and tagging of liver's intraoperative live views via CNN for minimal invasive surgery[J]. J Biomed Inform, 2020, 106: 103430. DOI: 10.1016/j.jbi.2020.103430.
[39]
Huang H, Zhou P, Li J, et al. Enhanced recovery after surgery in primary liver cancer patients undergoing hepatectomy: experience from a large tertiary hospital in China[J]. BMC Surg, 2023, 23(1): 185. DOI: 10.1186/s12893-023-02040-4.
[40]
Kehlet H. Multimodal approach to control postoperative pathophysiology and rehabilitation[J]. Br J Anaesth, 1997, 78(5): 606-617. DOI: 10.1093/bja/78.5.606.
[41]
Melloul E, Hübner M, Scott M, et al. Guidelines for perioperative care for liver surgery: enhanced recovery after surgery (ERAS) society recommendations[J]. World J Surg, 2016, 40(10): 2425-2440. DOI: 10.1007/s00268-016-3700-1.
[42]
Hu Y, Hsu AW, Strong VE. Enhanced recovery after major gastrectomy for cancer[J]. Ann Surg Oncol, 2021, 28(12): 6947-6954. DOI: 10.1245/s10434-021-09906-y.
[43]
Li N, Liu Y, Chen H, et al. Efficacy and safety of enhanced recovery after surgery pathway in minimally invasive colorectal cancer surgery: a systemic review and meta-analysis[J]. J Laparoendosc Adv Surg Tech A, 2023, 33(2): 177-187. DOI: 10.1089/lap.2022.0349.
[44]
Reyes MP, Pérez BS, González CS, et al. Implementation of an ERAS protocol on cirrhotic patients in liver resection: a cohort study[J]. Updates Surg, 2024, 76(3): 889-897. DOI: 10.1007/s13304-024-01769-8.
[45]
Fujio A, Miyagi S, Tokodai K, et al. Effects of a new perioperative enhanced recovery after surgery protocol in hepatectomy for hepatocellular carcinoma[J]. Surg Today, 2020, 50(6): 615-622. DOI: 10.1007/s00595-019-01930-6.
[46]
Liang X, Ying H, Wang H, et al. Enhanced recovery care versus traditional care after laparoscopic liver resections: a randomized controlled trial[J]. Surg Endosc, 2018, 32(6): 2746-2757. DOI: 10.1007/s00464-017-5973-3.
[47]
Ljungqvist O, Scott M, Fearon KC. Enhanced recovery after surgery: a review[J]. JAMA Surg, 2017, 152(3): 292-298. DOI: 10.1001/jamasurg.2016.4952.
[48]
Zeng X, Tao H, Dong Y, et al. Impact of three-dimensional reconstruction visualization technology on short-term and long-term outcomes after hepatectomy in patients with hepatocellular carcinoma: a propensity-score-matched and inverse probability of treatment-weighted multicenter study[J]. Int J Surg, 2024, 110(3): 1663-1676. DOI: 10.1097/JS9.0000000000001047.
[49]
Yang J, Rhu J, Lim S, et al. Impact of virtual reality education on disease-specific knowledge and anxiety for hepatocellular carcinoma patient scheduled for liver resection: a randomized controlled study[J]. Int J Surg, 2024, 110(5): 2810-2817. DOI: 10.1097/JS9.0000000000001197.
[50]
Zhu W, Zeng X, Hu H, et al. Perioperative and disease-free survival outcomes after hepatectomy for centrally located hepatocellular carcinoma guided by augmented reality and indocyanine green fluorescence imaging: a single-center experience[J]. J Am Coll Surg, 2023, 236(2): 328-337. DOI: 10.1097/XCS.0000000000000472.
[51]
Zhang JZ, Yang CX, Gao S, et al. Three-dimensional visualization and evaluation of hilar cholangiocarcinoma resectability and proposal of a new classification[J]. World J Surg Oncol, 2023, 21(1): 239. DOI: 10.1186/s12957-023-03126-2.
[52]
袁文康, 张超. 三维打印在肝胆胰外科领域的研究及进展[J]. 中华肝胆外科杂志, 2023, 29(2): 148-151. DOI: 10.3760/cma.j.cn113884-20220810-00328.
[53]
Huber T, Huettl F, Tripke V, et al. Experiences with three-dimensional printing in complex liver surgery[J]. Ann Surg, 2021, 273(1): e26-e27. DOI: 10.1097/SLA.0000000000004348.
[54]
Liu F, Wang H, Ma W, et al. Short-and long-term outcomes of indocyanine green fluorescence navigation-versus conventional-laparoscopic hepatectomy for hepatocellular carcinoma: a propensity score-matched, retrospective, cohort study[J]. Ann Surg Oncol, 2023, 30(4): 1991-2002. DOI: 10.1245/s10434-022-13027-5.
[55]
成功, 王逻逻, 阮一, 等. 虚拟现实技术在肝脏外科术前计划制定中的应用[J]. 现代实用医学, 2022, 34(2): 160-162. DOI: 10.3969/j.issn.1671-0800.2022.02.008.
[1] 黎伟忠, 黎嘉历, 张映南, 莫灿荣. 改良Glisson鞘外阻断在腹腔镜解剖性左半肝切除术中的应用研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(04): 453-456.
[2] 张腾, 韩威, 冯章东. 肝内胆管结石不同微创手术方式的临床研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(04): 384-387.
[3] 张光亚, 方荣喜, 吴鹏, 肖虎. 腹腔镜下不同入肝血流阻断肝切除治疗原发性肝癌的近中期随访比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(04): 376-379.
[4] 刘伟博, 李林, 张玉斌. ERAS理念下的经脐单孔腹腔镜胆囊切除术对患者术后恢复的影响[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(03): 278-281.
[5] 张小松, 马俊永, 李锡锋, 施乐华, 沈锋. 腹腔镜鞘内解剖性右半肝切除联合区域淋巴结清扫[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(03): 245-245.
[6] 沈锋, 王葵, 刘建伟. 我国腹腔镜肝癌手术治疗现状、问题与发展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(03): 237-240.
[7] 蔡建强, 毕新宇, 徐博文. 我国腹腔镜肝癌手术的难点与对策[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(03): 241-244.
[8] 卢超, 陈波, 邢志祥, 周鹏, 王帅. 不同入路下腹腔镜解剖性肝脏切除术治疗肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(03): 254-257.
[9] 盛海涛, 窦明睿, 王俊杰, 修小龙, 杨建茂, 董长城. 基于CT三维可视化技术的个体化肝分段在解剖性肝切除术中的应用[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(03): 258-261.
[10] 李菊, 王留芳, 叶春伟, 刘玉芹, 和志梅. 预康复在泌尿系统恶性肿瘤患者中的研究进展[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(04): 514-520.
[11] 唐玥, 陈家璐, 覃德龙, 李宗龙, 汤朝晖, 全志伟. 腹腔镜肝切除治疗复发性肝癌的焦点与难点问题探讨[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(05): 667-672.
[12] 吴金柱, 王锐, 朱国栋, 蔡卫华. 吲哚菁绿荧光导航腹腔镜肝右前叶切除术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(05): 802-802.
[13] 平文俊, 李江涛, 陈国栋. 机器人肝门部胆管癌根治术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(05): 804-804.
[14] 麦吾兰江·麦麦提, 吐尔洪江·吐逊. 低中心静脉压技术及其在腹腔镜肝切除术中应用进展[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(04): 528-535.
[15] 龚财芳, 姚娟, 李欢, 熊永福, 赵俊宇, 游川. 肝癌肝切除术后胃肠功能障碍的诊治和防治进展[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(04): 640-645.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?