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中华肝脏外科手术学电子杂志 ›› 2015, Vol. 04 ›› Issue (01) : 13 -16. doi: 10.3877/cma.j.issn.2095-3232.2015.01.004

所属专题: 文献

临床研究

循肝脏重要脉管精准肝切除治疗肝胆肿瘤
李健1, 孙玉岭1,(), 朱荣涛1, 张弛弦1, 马秀现1   
  1. 1. 450052 郑州大学第一附属医院肝胆外科 郑州大学肝胆胰疾病研究所
  • 收稿日期:2014-09-28 出版日期:2015-02-10
  • 通信作者: 孙玉岭
  • 基金资助:
    国家自然科学基金(81100304)

Precise hepatectomy following important liver vessels for hepatobiliary tumors

Jian Li1, Yuling Sun1,(), Rongtao Zhu1, Chixian Zhang1, Xiuxian Ma1   

  1. 1. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Zhengzhou University, Institute of Hepatobiliary and Pancreatic Diseases of Zhengzhou University, Zhengzhou 450052, China
  • Received:2014-09-28 Published:2015-02-10
  • Corresponding author: Yuling Sun
  • About author:
    Corresponding author: Sun Yuling, Email:
引用本文:

李健, 孙玉岭, 朱荣涛, 张弛弦, 马秀现. 循肝脏重要脉管精准肝切除治疗肝胆肿瘤[J/OL]. 中华肝脏外科手术学电子杂志, 2015, 04(01): 13-16.

Jian Li, Yuling Sun, Rongtao Zhu, Chixian Zhang, Xiuxian Ma. Precise hepatectomy following important liver vessels for hepatobiliary tumors[J/OL]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2015, 04(01): 13-16.

目的

探讨循肝脏重要脉管精准肝切除在肝胆肿瘤治疗中的应用价值。

方法

回顾性分析2012年1月至2013年1月在郑州大学第一附属医院行循肝脏重要脉管精准切除术治疗的26例肝胆肿瘤患者临床资料。其中男14例,女12例;年龄20~66岁,中位年龄56岁。所有患者均签署知情同意书,符合医学伦理学规定。根据术前影像学检查及术中探查结果选择紧邻肿瘤的重要脉管为解剖引导,预测切肝平面。术中超声检查明确肿瘤与门静脉分支、肝静脉、下腔静脉等肝脏重要脉管解剖位置的关系。应用超声吸引刀、双极电凝等手术器械完成精准肝切除。

结果

26例患者均顺利完成手术,肿瘤全部完整切除。其中行左半肝+尾状叶切除7例,右半肝切除6例,肝中叶切除4例,扩大右半肝切除3例,肝Ⅳb、Ⅴ段切除2例,肝右前叶切除2例,左半肝+尾状叶切除+胰十二指肠切除1例,肝尾状叶切除+肝后下腔静脉人工血管置换1例。平均手术时间(5.5±0.4) h,术中出血量(580±59) ml,住院时间(19±3) d。术后患者无发生大出血、肝衰竭等严重并发症,术后腹腔感染2例,胆漏1例,经抗感染及引流治疗治愈。

结论

循肝脏重要脉管精准肝切除是治疗肝胆肿瘤安全、有效的手术方法。

Objective

To investigate the application value of precise hepatectomy following important liver vessels for hepatobiliary tumors.

Methods

Clinical data of 26 patients with hepatobiliary tumors in the First Affiliated Hospital of Zhengzhou University from January 2012 to January 2013 were analyzed retrospectively. There were 14 males and 12 females with the age ranging from 20 to 66 years old and a median of 56 years old. The informed consents of all patients were obtained and local ethical committee approval had been received. The important vessels closely adjacenting to tumors were selected as the guide line for dissection according to the preoperative imaging examinations and intraoperative exploration results and the liver resecting surface was predicted. The anatomic relations between the tumor and the important liver vessels such as portal branch, hepatic vein, inferior vena cava were defined by intraoperative ultrasound. Precise hepatectomy were performed with surgical instruments such as cavitron ultrasonic surgical aspirator, bipolar coagulator.

Results

The operations of 26 patients were performed successfully and the tumors were resected completely, including left hemihepatectomy + caudate lobectomy (n=7), right hemihepatectomy (n=6), mesohepatectomy (n=4), extended right hemihepatectomy (n=3), segment Ⅳb, V hepatectomy (n=2), hepatic right anterior lobectomy (n=2), left hemihepatectomy + caudate lobectomy + pancreaticoduodenectomy (n=1), caudate lobectomy + artificial vessel replacement of retrohepatic inferior vena cava (n=1). The average operative time was (5.3±0.4) h, the intraoperative blood loss was (580±59) ml and the length of hospital stay was (19±3) d. No severe complications such as massive haemorrhage, liver failure were observed after operation. Abdominal infection was observed in 2 cases and biliary leakage in 1 case after operation and all were cured by anti-infection and drainage treatments.

Conclusion

Precise hepatectomy following the important liver vessels is a safe and effective surgical procedure for hepatobiliary tumors.

图1 一例肝中叶肿瘤患者肝切除术前后上腹部CT表现
[1]
董家鸿,杨世忠.现代科技在精准肝切除中的综合应用[J].肝胆外科杂志,2010, 18(1):57-59.
[2]
田秉璋,吴金术,沈贤波,等.循肝中静脉的解剖性半肝切除:附58例报告[J].中国普通外科杂志,2013, 22(1):14-17.
[3]
Bodzin AS, Leiby BE, Ramirez CG, et al. Liver resection using cavitron ultrasonic surgical aspirator (CUSA) versus harmonic scalpel: a retrospective cohort study[J]. Int J Surg, 2014, 12(5):500-503.
[4]
Shiba H, Haruki K, Futagawa Y, et al. Central bisegmentectomy for malignant liver tumors: experience in 8 patients[J]. Int Surg, 2014, 99(5):612-615.
[5]
Zuo CH, Qiu XX, Ouyang YZ, et al. Mesohepatectomy for the treatment of patients with centrally located hepatocellular carcinoma[J]. Mol Clin Oncol, 2014, 2(5):833-838.
[6]
Kishi Y, Saiura A, Yamamoto J, et al. Is hepatic resection for recurrent or persistent hepatocellular carcinoma justified?[J]. Hepatogastroenterology, 2012, 59(119):2255-2259.
[7]
杨世忠,张文智,蔡守旺,等.计算机辅助手术规划系统在精准肝切除中的应用价值[J].中华消化外科杂志,2010, 9(1):31-34.
[8]
Fancellu A, Rosman AS, Sanna V, et al. Meta-analysis of trials comparing minimally-invasive and open liver resections for hepatocellular carcinoma[J]. J Surg Res, 2011, 171(1):e33-45.
[9]
Gaillard M, Tranchart H, Dagher I. Laparoscopic liver resections for hepatocellular carcinoma: current role and limitations[J]. World J Gastroenterol, 2014, 20(17):4892-4899.
[10]
董家鸿,郑树森,陈孝平,等.肝切除术前肝脏储备功能评估的专家共识(2011版)[J].中华消化外科杂志,2011, 10(1):20-25.
[11]
匡铭,汤地,王晔,等.三维手术模拟系统在肝癌患者精准肝切除中的应用[J].中国普外基础与临床杂志,2011, 18(7):682-687.
[12]
Azoulay D. Resection for hepatocellular carcinoma with hepatic vein tumour thrombus: pushing the limits beyond the guidelines frontiers[J]. J Hepatol, 2014, 61(3):462-463.
[13]
Wang HQ, Yang J, Yan LN, et al. Liver resection in hepatitis B related-hepatocellular carcinoma: clinical outcomes and safety in elderly patients[J]. World J Gastroenterol, 2014, 20(21):6620-6625.
[14]
Shen WF, Wu L, Dong H, et al. Hepatic resection for multiple hepatocellular carcinoma less than 5 cm: a prospective comparative study[J]. Hepatogastroenterology, 2014, 61(129):173-180.
[15]
马渝城,严律南.微创理念下腹腔镜肝切除的现状分析[J/CD].中华肝脏外科手术学电子杂志,2013, 2(6):358-362.
[16]
郭鹏,李建伟,郑树国.腹腔镜解剖性右半肝切除术(附视频)[J/CD].中华肝脏外科手术学电子杂志,2013, 2(6):405-406.
[17]
Jia C, Wang H, Chen Y, et al. Anatomic liver resection of segments 6, 7, and 8 by the method of selective occlusion of hepatic inflow[J]. Indian J Surg, 2014, 76(2):159-161.
[18]
Kokudo T, Hasegawa K, Yamamoto S, et al. Surgical treatment of hepatocellular carcinoma associated with hepatic vein tumor thrombosis[J]. J Hepatol, 2014, 61(3):583-588.
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