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中华肝脏外科手术学电子杂志 ›› 2023, Vol. 12 ›› Issue (06) : 597 -601. doi: 10.3877/cma.j.issn.2095-3232.2023.06.002

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肝细胞癌转化治疗方式
杜锡林(), 谭凯, 贺小军, 白亮亮, 赵瑶瑶   
  1. 710038 西安,空军军医大学第二附属医院普通外科
    710038 西安,空军军医大学第二附属医院继续教务办公室
  • 收稿日期:2023-08-20 出版日期:2023-12-10
  • 通信作者: 杜锡林
  • 基金资助:
    陕西省自然科学基础研究计划(2020JM-337)

Conversion therapies for hepatocellular carcinoma

Xilin Du(), Kai Tan, Xiaojun He   

  • Received:2023-08-20 Published:2023-12-10
  • Corresponding author: Xilin Du
引用本文:

杜锡林, 谭凯, 贺小军, 白亮亮, 赵瑶瑶. 肝细胞癌转化治疗方式[J/OL]. 中华肝脏外科手术学电子杂志, 2023, 12(06): 597-601.

Xilin Du, Kai Tan, Xiaojun He. Conversion therapies for hepatocellular carcinoma[J/OL]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(06): 597-601.

原发性肝癌是全球范围内常见的恶性肿瘤之一,发病率居第6位,肿瘤致死原因居第4位[1]。我国原发性肝癌新发和死亡人数约占全球的一半,其中肝细胞癌(肝癌)最为常见。目前,肝癌的治疗方式多种多样,其中手术治疗是最主要的治疗方式之一,但大多数患者初诊时病情已达中晚期,失去了根治性手术切除的机会[2]。此外,我国作为乙型病毒性肝炎(乙肝)大国,大多数肝癌患者合并肝硬化病史,肝脏储备功能差,对于术后残肝体积要求也较高。转化治疗通过改善肝功能,降低肿瘤分期和增加剩余肝体积的途经将不可切除肝癌转变为可切除肝癌。转化治疗理念已经深入人心,并取得了显著的疗效。目前转化治疗的方式也已经初步达成了共识[3],但仍有很多细节的问题需要探讨,笔者就目前肝癌转化治疗方式的现状和展望进行思考和概述,供临床医师参考。

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