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中华肝脏外科手术学电子杂志 ›› 2019, Vol. 08 ›› Issue (04) : 320 -324. doi: 10.3877/cma.j.issn.2095-3232.2019.04.010

所属专题: 文献

临床研究

加速康复外科在腹腔镜肝囊型包虫病根治术中的应用
孟塬1, 巴合提·卡力甫1, 马志刚1, 王锦国1, 卢爽1, 依马木·阿布拉1, 宋魏1, 田广磊1, 马明1, 陈雄1,()   
  1. 1. 830001 乌鲁木齐,新疆维吾尔自治区人民医院肝胆外科
  • 收稿日期:2019-03-18 出版日期:2019-08-10
  • 通信作者: 陈雄
  • 基金资助:
    自治区科技支疆计划项目(2017E0271)

Application of enhanced recovery after surgery in laparoscopic radical resection of hepatic cystic echinococcosis

Yuan Meng1, Kalifu Baheti1, Zhigang Ma1, Jinguo Wang1, Shuang Lu1, Abula Yimamu1, Wei Song1, Guanglei Tian1, Ming Ma1, Xiong Chen1,()   

  1. 1. Department of Hepatobiliary Surgery, Xinjiang Uygur Municipal People's Hospital, Urumqi 830001, China
  • Received:2019-03-18 Published:2019-08-10
  • Corresponding author: Xiong Chen
  • About author:
    Corresponding author: Chen Xiong, Email:
引用本文:

孟塬, 巴合提·卡力甫, 马志刚, 王锦国, 卢爽, 依马木·阿布拉, 宋魏, 田广磊, 马明, 陈雄. 加速康复外科在腹腔镜肝囊型包虫病根治术中的应用[J/OL]. 中华肝脏外科手术学电子杂志, 2019, 08(04): 320-324.

Yuan Meng, Kalifu Baheti, Zhigang Ma, Jinguo Wang, Shuang Lu, Abula Yimamu, Wei Song, Guanglei Tian, Ming Ma, Xiong Chen. Application of enhanced recovery after surgery in laparoscopic radical resection of hepatic cystic echinococcosis[J/OL]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2019, 08(04): 320-324.

目的

探讨加速康复外科(ERAS)在腹腔镜肝囊型包虫病根治术中的应用价值。

方法

回顾性分析2016年1月至2017年11月在新疆维吾尔自治区人民医院行腹腔镜完整包虫外囊切除术的38例肝囊型包虫病患者临床资料。其中男24例,女14例;年龄17~70岁,中位年龄46岁。患者均签署知情同意书,符合医学伦理学规定。采用ERAS方案治疗者24例,设为ERAS组;采用传统方案治疗者14例,设为传统组。两组患者围手术期情况比较采用t检验,率的比较采用χ2检验或Fisher确切概率法。

结果

ERAS组术后下床活动时间、术后肛门排气时间和术后引流管拔除时间分别为(1.5±0.4)、(1.4±0.6)、(6.4±1.1)d,明显少于传统组的(3.4±0.6)、(2.6±0.5)、(8.2±1.3)d(t=-2.56、-3.91、-2.75;P<0.05)。ERAS组手术时间和术中出血量分别为(132±25)min、(240±30)ml,传统组相应为(26±21)min、(191±15)ml,差异无统计学意义(t=0.68、0.80;P>0.05)。ERAS组中转开腹2例,传统组无中转开腹,差异无统计学意义(P>0.05)。ERAS组、传统组术后并发症发生率分别为17%(4/24)、14%(2/14),差异无统计学意义(χ2=0.846,P>0.05)。随访期间两组均无复发,无发生腹腔积液、重大心脑血管并发症。

结论

ERAS应用于腹腔镜下肝囊型包虫病根治术有效,可加快患者术后康复,缩短住院时间,且不增加手术风险和术后并发症发生。

Objective

To explore the application value of enhanced recovery after surgery (ERAS) in the laparoscopic radical resection of hepatic cystic echinococcosis.

Methods

Clinical data of 38 patients with hepatic cystic echinococcosis undergoing laparoscopic total external cystectomy in Xinjiang Uygur Municipal People's Hospital from January 2016 to November 2017 were retrospectively analyzed. Among them, 24 patients were male and 14 female, aged 17-70 years with a median age of 46 years. The informed consents of all patients were obtained and the local ethical committee approval was received. 24 patients who were treated with ERAS program were assigned into the ERAS group and 14 patients receiving traditional therapy were allocated in the traditional group. The perioperative conditions were statistically compared between two groups by t test. The rate comparison was performed by Chi-square test or Fisher's exact test.

Results

The postoperative off-bed ambulation time, postoperative exhaust time and postoperative removal time of drainage tube in the ERAS group were (1.5±0.4), (1.4±0.6) and (6.4±1.1) d, significantly shorter than (3.4±0.6), (2.6±0.5) and (8.2±1.3) d in the traditional group (t=-2.56, -3.91, -2.75; P<0.05). In the ERAS group, the operation time and intraoperative blood loss were (132±25) min and (240±30) ml, which did not significantly differ from (26±21) min and (191±15) ml in the traditional group (t=0.68, 0.80; P>0.05). In the ERAS group, 2 cases were converted to open surgery and none in the traditional group, where no significant difference was observed (P>0.05). The incidence of postoperative complications in the ERAS and traditional groups was 17% (4/24) and 14% (2/14), respectively, where no significant difference was observed (χ2=0.846, P>0.05). During the follow-up, no recurrence, peritoneal effusion or major cardiovascular and cerebrovascular complication occurred.

Conclusions

ERAS is an efficacious approach for laparoscopic radical resection of hepatic cystic echinococcosis, which can accelerate postoperative recovery and shorten the length of hospital stay without increasing the surgical risk and postoperative complications.

表1 ERAS组和传统组肝包虫病根治术患者术中及术后情况比较(±s
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