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中华肝脏外科手术学电子杂志 ›› 2022, Vol. 11 ›› Issue (04) : 422 -425. doi: 10.3877/cma.j.issn.2095-3232.2022.04.020

综述

神经内分泌肿瘤肝转移诊治进展
庄荣源1, 周宇红1,()   
  1. 1. 200032 上海,复旦大学附属中山医院肿瘤内科
  • 收稿日期:2022-04-20 出版日期:2022-08-10
  • 通信作者: 周宇红

Progress in diagnosis and treatments for neuroendocrine liver metastases

Rongyuan Zhuang1, Yuhong Zhou1()   

  • Received:2022-04-20 Published:2022-08-10
  • Corresponding author: Yuhong Zhou
引用本文:

庄荣源, 周宇红. 神经内分泌肿瘤肝转移诊治进展[J/OL]. 中华肝脏外科手术学电子杂志, 2022, 11(04): 422-425.

Rongyuan Zhuang, Yuhong Zhou. Progress in diagnosis and treatments for neuroendocrine liver metastases[J/OL]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2022, 11(04): 422-425.

神经内分泌肿瘤(neuroendocrine neoplasm, NEN)是一类少见的,起源于神经内分泌细胞和肽能神经元的恶性肿瘤。每年NEN发病率约6.98/10万,女性略多,占52.7%[1]。NEN可发生于身体的任何部位,最常见于胃、肠、胰等消化系统器官。肝脏是神经内分泌肿瘤最常见的转移部位,28%~77%的NEN患者会发生肝转移[2]。神经内分泌肿瘤肝转移(neuroendocrine liver metastases,NELM)严重影响患者的生活质量和预后。近年来,病理学和影像学诊断技术的发展,多学科综合治疗理念的推广以及新的治疗手段和治疗策略的改进,极大提高了NELM的诊治水平,改善了患者的生活质量,延长了患者的总生存期。

表1 2019年WHO(第5版)胃肠道/肝胆胰NEN分类和分级标准[3]
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