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中华肝脏外科手术学电子杂志 ›› 2024, Vol. 13 ›› Issue (01) : 1 -4. doi: 10.3877/cma.j.issn.2095-3232.2024.01.001

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胆道闭锁小儿肝移植手术时机、术式和疗效
夏普开提·甫拉提, 吐尔洪江·吐逊, 温浩(), 姚刚   
  1. 830054 乌鲁木齐,新疆医科大学第一附属医院消化血管外科中心 肝脏·腹腔镜外科
  • 收稿日期:2023-10-04 出版日期:2024-02-10
  • 通信作者: 温浩
  • 基金资助:
    国家自然科学基金(82270632); 省部共建中亚高发病成因与防治国家重点实验室包虫病专项(SKL-HIDCA-2020-BC4)

Timing, procedures and efficacy of liver transplantation in children with biliary atresia

Fulati Xiapukaiti·, Tuxun Tuerhongjiang·, Hao Wen(), Gang Yao   

  1. Digestive Vascular Surgery Center, Department of Liver & Laparoscopic Surgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Received:2023-10-04 Published:2024-02-10
  • Corresponding author: Hao Wen
引用本文:

夏普开提·甫拉提, 吐尔洪江·吐逊, 温浩, 姚刚. 胆道闭锁小儿肝移植手术时机、术式和疗效[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(01): 1-4.

Fulati Xiapukaiti·, Tuxun Tuerhongjiang·, Hao Wen, Gang Yao. Timing, procedures and efficacy of liver transplantation in children with biliary atresia[J/OL]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2024, 13(01): 1-4.

胆道闭锁是由于肝外与肝内胆管发生进行性纤维炎性梗阻而导致的胆汁淤积性肝硬化,并最终以肝衰竭为结局的一类疾病,是小儿肝移植手术的常见适应证。本文将探讨胆道闭锁的发病机制、诊断方法、肝移植手术时机、手术方式及术后并发症;同时探讨小儿肝移植的现状及发展。

Biliary atresia is a category of disease caused by biliary cirrhosis due to progressive fibro-inflammatory obstruction of extrahepatic and intrahepatic bile ducts, and eventually progresses into liver failure. It is a common indication for liver transplantation in children. In this article, the pathogenesis, diagnosis of biliary atresia, timing, procedures and postoperative complications of liver transplantation were illustrated. Meantime, current status and development of pediatric liver transplantation were discussed.

图1 胆道闭锁的分型注:Ⅰa为胆总管下端闭锁;Ⅰb为胆总管高位闭锁;Ⅱa为胆囊至十二指肠间的胆管开放,而肝管完全缺损或呈纤维条絮状;Ⅱb为肝外胆管完全闭锁;Ⅱc为肝管闭锁、胆管缺如;Ⅲa为肝管扩张型;Ⅲb为微细肝管型;Ⅲc为胆湖状肝管型
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