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中华肝脏外科手术学电子杂志

中华肝脏外科手术学电子杂志 ›› 2015, Vol. 04 ›› Issue (06) : 357 -359. doi: 10.3877/cma.j.issn.2095-3232.2015.06.008

所属专题： 文献；

临床研究

肝细胞癌经导管动脉化疗栓塞术后紫尿袋症患者的诊治体会
瞿虎1, 徐丽南2, 王晶3, 何科3,†(), 苏中振4, 江春强1   
  1. 1. 510655　广州，中山大学附属第六医院泌尿外科
    2. 510655　广州，中山大学附属第六医院妇产科生殖中心
    3. 510080　广州，中山大学附属第一医院妇产科
    4. 510630　广州，中山大学附属第三医院超声介入科
  • 收稿日期:2015-10-02 出版日期:2015-12-10
  • 通信作者: 何科
  • 基金资助:
    国家自然科学基金(81302550)

Diagnosis and treatment experiences of purple urine bag syndrome following transcatheter arterial chemoembolization for hepatocellular carcinoma

Hu Qu1, Linan Xu2, Jing Wang3, Ke He3,†(), Zhongzhen Su4, Chunqiang Jiang1   

  1. 1. Department of Urology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China
    2. Reproductive Center of Department of Obstetrics and Gynecology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China
    3. Department of Obstetrics and Gynecology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
    4. Department of Interventional Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
  • Received:2015-10-02 Published:2015-12-10
  • Corresponding author: Ke He
  • About author:
    Corresponding author:He Ke, Email:
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引用本文：

瞿虎, 徐丽南, 王晶, 何科, 苏中振, 江春强. 肝细胞癌经导管动脉化疗栓塞术后紫尿袋症患者的诊治体会[J]. 中华肝脏外科手术学电子杂志, 2015, 04(06): 357-359.

Hu Qu, Linan Xu, Jing Wang, Ke He, Zhongzhen Su, Chunqiang Jiang. Diagnosis and treatment experiences of purple urine bag syndrome following transcatheter arterial chemoembolization for hepatocellular carcinoma[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2015, 04(06): 357-359.

目的

探讨肝细胞癌（肝癌）TACE治疗术后紫尿袋症的诊断及治疗方法。

方法

回顾性分析2012年1月至2014年5月在中山大学附属第六医院接受肝癌TACE术的117例患者中，术后发生紫尿袋症的13例患者临床资料。其中男4例，女9例；年龄35～68岁，中位年龄53岁；肿瘤直径≤5 cm 8例，>5 cm 5例，TACE操作时间≤30 min 6例，>30 min 7例。所有患者均签署知情同意书，符合医学伦理学规定。以TACE术后尿袋中尿液染色呈粉红色至紫色，且尿常规检查未见血尿作为诊断标准。

结果

本组肝癌TACE术后患者紫尿袋症发生率为11.1%（13/117）。确诊紫尿袋症后予酸化尿液、水化治疗、定期更换尿管及尿袋、改善胃肠道功能等综合治疗后治愈，均未行抗感染治疗。本组患者导尿管平均留置时间（12±3）d。

结论

肝癌TACE术后患者发生紫尿袋症并不少见，应当引起重视。其治疗以酸化尿液、水化治疗及改善胃肠道功能为主。

关键词: 肝肿瘤, 放射学，介入性, 紫尿袋症
Objective

To investigate the diagnosis and treatment of purple urine bag syndrome following transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).

Methods

Clinical data of 13 patients who developed purple urine bag syndrome out of 117 patients undergoing TACE for HCC in the Sixth Affiliated Hospital of Sun Yat-sen University between January 2012 and May 2014 were retrospectively studied. Among the 13 patients, 4 were males and 9 were females with the age ranging from 35 to 68 years old and the median of 53 years old. The tumor diameter was ≤5 cm in 8 cases and was > 5 cm in 5 cases. The operative duration of TACE was ≤30 min in 6 cases and was >30 min in 7 cases. The informed consents of all patients were obtained and the local ethical committee approval had been received. The diagnostic criteria was pink to purple urine in the urine bag after TACE and no blood urine detected by urine routine test.

Results

The incidence of purple urine bag syndrome following TACE was 11.1% (13/117). After purple urine bag syndrome was confirmed, the patients were given the comprehensive therapy of urine acidification, rehydration, regular change of urinary catheter and urine bag, and gastrointestinal function improvement. No anti-infective therapy was given. The average indwelling time of urinary catheter was (12±3) d.

Conclusions

It is not a rare case for purple urine bag syndrome following TACE for HCC, thus it should be taken seriously. The treatment mainly includes urine acidification, rehydration and gastrointestinal function improvement.

Key words: Liver neoplasms, Radiology, interventional, Purple urine bag syndrome
图1 紫尿袋症患者尿液颜色
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