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中华肝脏外科手术学电子杂志 ›› 2024, Vol. 13 ›› Issue (03) : 270 -275. doi: 10.3877/cma.j.issn.2095-3232.2024.03.004

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肝硬化门静脉高压症门静脉压力无创测量进展
刘起帆1, 蒋安1,()   
  1. 1. 710004 西安交通大学第二附属医院移植外科
  • 收稿日期:2024-01-24 出版日期:2024-06-10
  • 通信作者: 蒋安
  • 基金资助:
    陕西省重点研发计划项目(2022SF-372)

Progress in non-invasive measurement of portal vein pressure in cirrhotic portal hypertension

Qifan Liu1, An Jiang1,()   

  1. 1. Department of Transplantation Surgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China
  • Received:2024-01-24 Published:2024-06-10
  • Corresponding author: An Jiang
引用本文:

刘起帆, 蒋安. 肝硬化门静脉高压症门静脉压力无创测量进展[J]. 中华肝脏外科手术学电子杂志, 2024, 13(03): 270-275.

Qifan Liu, An Jiang. Progress in non-invasive measurement of portal vein pressure in cirrhotic portal hypertension[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2024, 13(03): 270-275.

食管静脉曲张破裂出血作为肝硬化门静脉高压症最常见、凶险的并发症,时刻威胁患者的生命健康。准确评估门静脉压力为肝硬化患者预防疾病发展、监测并发症、选择治疗策略以及评估预后等提供重要依据。目前肝静脉压力梯度(HVPG)仍是诊断门静脉高压症的金标准,但此检查为有创操作,局限性及操作风险较大。近年来无创测量门静脉的方法取得较多进展。本文将对门静脉压力无创性检测方法及应用前景进行阐述和介绍。

Esophageal variceal bleeding, as the most common and severe complication of liver cirrhosis and portal hypertension, persistenly threatens the life and health of patients. Accurate evaluation of portal vein pressure provides valuable evidence for preventing disease progression, monitoring complications, choosing treatment strategies and evaluating clinical prognosis in patients with liver cirrhosis. At present, the hepatic venous pressure gradient (HVPG) remains the gold standard for the diagnosis of portal hypertension, whereas it is an invasive procedure with limitations and surgical risks. In recent years, certain progress has been made in non-invasive measurement of portal vein pressure. In this article, non-invasive detection method of portal vein pressure and its application prospect were illustrated.

图1 脾-肝指数放射性核素检测[7]注:a为前视图,红线为最长肝长度;b为前视图,右肝叶中心25像素感兴趣区域的平均肝数(红方);c为矢状面,脾中心25像素感兴趣区域(蓝色方块)的平均脾计数
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