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中华肝脏外科手术学电子杂志 ›› 2024, Vol. 13 ›› Issue (04) : 472 -480. doi: 10.3877/cma.j.issn.2095-3232.2024.04.006

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胰腺术后出血原因及诊治策略
王冬澳1, 林超1, 鄂长勇1,()   
  1. 1. 130033 长春,吉林大学白求恩第三医院肝胆胰外科
  • 收稿日期:2024-03-11 出版日期:2024-08-10
  • 通信作者: 鄂长勇
  • 基金资助:
    吉林省科技厅项目(20200403082SF,YDZJ202301ZYTS064)

Causes, diagnosis and treatment of postoperative pancreatic hemorrhage

Dongao Wang1, Chao Lin1, Changyong E1,()   

  1. 1. Department of Hepatobiliary and Pancreatic Surgery, the Third Bethune Hospital of Jilin University, Changchun 130033, China
  • Received:2024-03-11 Published:2024-08-10
  • Corresponding author: Changyong E
引用本文:

王冬澳, 林超, 鄂长勇. 胰腺术后出血原因及诊治策略[J]. 中华肝脏外科手术学电子杂志, 2024, 13(04): 472-480.

Dongao Wang, Chao Lin, Changyong E. Causes, diagnosis and treatment of postoperative pancreatic hemorrhage[J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2024, 13(04): 472-480.

出血是胰腺术后较为危险的并发症,因其发生迅速及诊断困难往往严重影响患者生命安全。根据疾病的不同,胰腺手术部位、手术方式不尽相同,PPH的原因也各有差异。随着手术方式的改良及介入技术的迅速发展,外科医师有了更多应对术后出血的方法,对于胰腺手术应制定应对围手术期出血的措施,通过实验室及影像学检查对病情作出诊断;采取术前减黄,输冰冻血浆、血小板、维生素K等改善凝血功能;术中精准操作避免损伤血管,选择恰当的方式如缝扎、切割闭合器等精确止血;术后保持引流管通畅,避免出血发现不及时或胰瘘引流不畅造成腹腔感染,及时复查腹部超声及腹部CT早期发现胰瘘并引流;高度警惕前哨出血现象,通过合理的措施降低胰腺术后出血的发生。本文就胰腺术后出血定义、原因,诊断及治疗措施作一综述,为临床提供进一步的参考。

Hemorrhage is a threatening complication after pancreatic surgery, which severely affects the life of patients due to rapid onset and difficult diagnosis. According to different types of diseases, the sites and approaches of pancreatic surgery, and the causes of postoperative pancreatic hemorrhage (PPH) significantly differ. With the improvement of surgical methods and rapid development of interventional techniques, surgeons have more options to treat postoperative bleeding. Corresponding measures should be taken to manage perioperative bleeding for pancreatic surgery. The diagnosis should be made based on laboratory and imaging examinations. Preoperative reduction of jaundice, transfusion of frozen plasma, platelets and vitamin K can be performed to improve coagulation function. Precise intraoperative operation can avoid vascular injury. Appropriate suturing, bandage and sealer should be adopted to achieve precise hemostasis. Postoperatively, the drainage tube should be maintained patent to avoid abdominal infection caused by delayed detection of bleeding or poor drainage of pancreatic fistula. Abdominal ultrasound and CT scan should be performed timely to identify pancreatic fistula and deliver drainage treatment. Extensive attention should be diverted to the phenomenon of sentinel bleeding. Effective measures should be taken to reduce the occurrence of PPH. In this article, the definition, causes, diagnosis and treatment of PPH were reviewed, aiming to provide further reference for clinical practice.

表1 国际胰腺外科学组对PPH的定义[4]
表2 PPH临床分级[4]
表3 胰腺术式和常见出血血管[13]
图1 胰腺术后出血的诊疗策略注:PPH为胰腺术后出血
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