近年来，随着分子靶向和免疫治疗的兴起，越来越多的中晚期肝细胞癌（HCC）患者从转化治疗中获益，并获得进行手术治疗的机会。现阶段，转化治疗在获益人群的评估选择、最佳转化策略的制定、手术方式和手术时机把握，以及术前精准规划和术中实时导航技术的研发已成为HCC转化治疗临床研究热点。其中，三维可视化技术是近期数字医学辅助实体肿瘤外科治疗的重要手段，也是解剖性肝切除术中实现精准规划和导航的核心工具。三维可视化技术利用立体评估，基于HCC转化治疗全程管理的理念，通过精准反映治疗效果，指导治疗决策，同时动态监测转化后目标肝脏解剖形态变化，规划最优手术方式。以三维可视化技术为代表的数字医学技术通过融合新颖影像技术算法，有望为系统治疗效果提供可靠预测。本文将综述以上相关技术在HCC转化治疗辅助决策中的应用，并阐述其临床实践意义。

In recent years, with the emergence of molecular targeting and immunotherapy, more and more patients with middle-advanced hepatocellular carcinoma (HCC) obtain benefits from translational therapy and achieve the opportunity of surgical treatment. At present, the evaluation and selection of eligible population, the formulation of the optimal translational strategy, surgical pattern and timing, precise preoperative planning and the research and development of intraoperative real-time navigation technology have become the hot spots in clinical research of HCC translational therapy. Among them, three-dimensional visualization technology is an important approach for digital medicine-assisted surgical treatment of solid tumors in recent years, which is also the core tool to realize precise planning and navigation in anatomical liver resection. Three-dimensional visualization technology utilizes three-dimensional evaluation, relies on the concept of full-course management of HCC translational treatment, precisely reflects therapeutic effect and guides treatment decision. In addition, it dynamically monitors the anatomical changes of the target liver after translational therapy, thereby formulating the optimal surgical approach. Digital medical technologies, represented by three-dimensional visualization technology, are expected to provide reliable prediction for systemic therapeutic effect by integrating novel imaging technological algorithms. In this article, the application of these technologies in the decision-making of HCC translational therapy was reviewed, and clinical practical significance was illustrated.